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[基于干扰素的细胞因子疗法治疗晚期肾细胞癌]

[Interferon-based cytokine therapy for advanced renal cell carcinoma].

作者信息

Takayama Tatsuya, Kai Fumitake, Sugiyama Takayuki, Furuse Hiroshi, Mugiya Soichi, Ozono Seiichiro

机构信息

The Department of Urology, Hamamatsu University School of Medicine.

出版信息

Hinyokika Kiyo. 2005 Aug;51(8):499-502.

PMID:16164263
Abstract

Among 126 patients diagnosed with metastatic renal cell carcinoma at Hamamatsu University or its affiliated hospital between 1978 and 2004, pretreatment features associated with a shorter survival in the multivariate analysis were in symptomatic status at diagnosis and in multiple organ metastasis. The 1- and 3-year survival rate in patients with these two prognostic factors were 22.3 and 0.3%, respectively. The style of treatment did not influenced survival in these patients. Therefore, an accurate assessment of their survival benefits both them and physician while it is urgent that we develop novel agents and strategy.

摘要

1978年至2004年间,在滨松大学及其附属医院被诊断为转移性肾细胞癌的126例患者中,多因素分析显示与较短生存期相关的预处理特征为诊断时出现症状以及多器官转移。具有这两个预后因素的患者1年和3年生存率分别为22.3%和0.3%。治疗方式对这些患者的生存期没有影响。因此,准确评估其生存获益对患者和医生都很重要,同时我们迫切需要开发新的药物和策略。

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