Perera G, Hay R
Department of Dermatology, King's College Hospital, Denmark Hill, Camberwell, London, SE5 9RS, UK.
J Eur Acad Dermatol Venereol. 2005 Sep;19(5):531-45. doi: 10.1111/j.1468-3083.2005.01296.x.
The emergence of bacterial resistance to commonly used antibiotics is not new. In this review we have tried to cover the ever increasing problems facing the treatment and containment of bacterial skin infections. We have tried to give an overview of the varied mechanisms by which bacteria gain and spread antimicrobial resistance, whilst dealing with the patterns of resistance exhibited by some of the commonly encountered organisms. Where there is evidence, we have formulated an approach on how to tackle antibiotic resistance. Where there is a lack of evidence we have formulated what we perceive to be appropriate guidelines.
细菌对常用抗生素产生耐药性并非新鲜事。在本综述中,我们试图涵盖治疗和控制细菌性皮肤感染所面临的日益增多的问题。我们试图概述细菌获得和传播抗微生物耐药性的各种机制,同时探讨一些常见病原体所表现出的耐药模式。在有证据的情况下,我们制定了应对抗生素耐药性的方法。在缺乏证据的情况下,我们制定了我们认为合适的指南。