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适应性混沌:轻度紊乱可能有助于控制重大疾病。

Adaptive chaos: mild disorder may help contain major disease.

作者信息

Golbin Alexander, Umantsev Alexander

机构信息

Sleep and Behavior Medicine Institute, 9700 N. Kenton Avenue, Skokie, IL 60076, USA.

出版信息

Med Hypotheses. 2006;66(1):182-7. doi: 10.1016/j.mehy.2005.06.031. Epub 2005 Sep 13.

Abstract

We have qualitatively analyzed different cases of human disorders and displacement activities of animals and hypothesize that some of them are examples of low-dimensional dynamical chaos in biological organisms. We also considered a biological organism in the framework of the control system theory and found that chaotic regime in one subsystem may be compensating for the loss of chaos in another subsystem for the sake of stability of the whole system. According to the hypothesis chaotic behavior of different organs sets in a human body as an alternative to serious diseases or even death. The principle of compensation was applied to different physiological systems with chaotic regimes to explain the adaptive nature of chaos there. Implications of the mechanism of adaptive chaos for sleep diseases, e.g., enuresis, and other potentially life threatening disorders of humans, e.g., RLS, are discussed in connection with the possibility to use these ideas for improved treatment strategies. The main conclusion is that adaptive disorders with chaotic symptoms should not be aggressively treated; if adaptive disorders are over treated, the whole organism may be thrown into a more regular state, which eventually will lead to a chronic disease or even death.

摘要

我们已对人类疾病的不同病例以及动物的替代活动进行了定性分析,并假设其中一些是生物有机体中低维动态混沌的实例。我们还在控制系统理论的框架内考虑了一个生物有机体,发现一个子系统中的混沌状态可能会为了整个系统的稳定性而补偿另一个子系统中混沌的丧失。根据这一假设,人体不同器官的混沌行为是严重疾病甚至死亡的一种替代情况。补偿原理被应用于具有混沌状态的不同生理系统,以解释其中混沌的适应性本质。结合将这些观点用于改进治疗策略的可能性,讨论了适应性混沌机制对睡眠疾病(如遗尿症)以及人类其他潜在危及生命的疾病(如不宁腿综合征)的影响。主要结论是,不应积极治疗具有混沌症状的适应性疾病;如果对适应性疾病过度治疗,整个有机体可能会陷入更规律的状态,最终将导致慢性病甚至死亡。

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