Añón R, Ibor P, Tomás-Ridocci M, Zaragoza A, Mora F, Moreno E, Benages A, Calvo B
Unidad de Motilidad Digestiva, Hospital Clínico Universitario Valencia.
Rev Esp Enferm Dig. 1992 May;81(5):307-12.
Twenty patients with the diagnosis of Zenker's diverticulum were studied clinically and manometrically. In 8 patients oropharyngeal clearance of liquid isotopic markers was done. In three, esophageal emptying of a marked meal was also studied. Clinically, sixteen patients had oropharyngeal dysphagia, while for remained asymptomatic. Dysphagia was severe in only five patients. In half of the patients there were signs of hiatus hernia and/or reflux. Pharyngo-sphincteric incoordination was present in 70% of cases with a mean resting pressure of the LES significantly lower than in controls. There were no differences among patients with or without reflux. Isotopic esophageal clearance was not useful as a test, as there were no significant differences with the control group. On the other hand, esophageal emptying of solid isotopic meals may show the persistence of food in the diverticular sac long time after the meal.
对20例诊断为Zenker憩室的患者进行了临床和测压研究。8例患者进行了液体同位素标记物的口咽清除试验。3例患者还研究了标记餐的食管排空情况。临床上,16例患者有口咽吞咽困难,其余患者无症状。只有5例患者吞咽困难严重。一半的患者有食管裂孔疝和/或反流的体征。70%的病例存在咽括约肌不协调,LES平均静息压力显著低于对照组。有反流和无反流的患者之间没有差异。同位素食管清除试验无用,因为与对照组没有显著差异。另一方面,固体同位素餐的食管排空可能显示餐后很长时间食物仍滞留在憩室囊中。