宫颈液中的人绒毛膜促性腺激素作为流产的预测指标。
Human chorionic gonadotropin in cervical fluid as a predictor of miscarriage.
作者信息
Takata Kayoko, Suganuma Nobuhiko, Wada Hisae, Takeuchi Kinya, Kitamura Kimiya, Kanayama Naohiro
机构信息
Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
出版信息
Fertil Steril. 2005 Sep;84(3):687-91. doi: 10.1016/j.fertnstert.2005.02.044.
OBJECTIVE
To determine whether the concentration of hCG in cervical fluid can predict miscarriage during early pregnancy.
DESIGN
Prospective clinical study.
SETTING
University hospital.
PATIENT(S): Ninety-nine women with singleton pregnancies, 17 of whom suffered a miscarriage.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Miscarriage and the cervical fluid/serum hCG concentration ratio.
RESULT(S): With a cutoff value of 1.0, the sensitivity, specificity, and positive and negative predictive values of the cervical fluid/serum hCG concentration ratio for predicting miscarriage were 88.2%, 94.9%, 83.3%, and 96.6%, respectively.
CONCLUSION(S): The cervical fluid/serum hCG concentration ratio might be a useful predictor of miscarriage during early pregnancy.
目的
确定宫颈液中hCG的浓度是否能预测早期妊娠期间的流产情况。
设计
前瞻性临床研究。
地点
大学医院。
患者
99名单胎妊娠女性，其中17人发生流产。
干预措施
无。
主要观察指标
流产情况及宫颈液/血清hCG浓度比值。
结果
以1.0为临界值时，宫颈液/血清hCG浓度比值预测流产的敏感性、特异性、阳性预测值和阴性预测值分别为88.2%、94.9%、83.3%和96.6%。
结论
宫颈液/血清hCG浓度比值可能是早期妊娠期间流产的有用预测指标。
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