Mankin Henry J, Hornicek Francis J, Ortiz-Cruz Eduardo, Villafuerte Jorge, Gebhardt Mark C
Orthopedic Oncology Service, Orthopedic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
J Clin Oncol. 2005 Sep 20;23(27):6756-62. doi: 10.1200/JCO.2005.15.255.
We have reviewed a series of 150 aneurysmal bone cysts treated over the last 20 years.
The lesions were principally located in the tibia, femur, pelvis, humerus, and spine and, in most cases, presented the imaging appearance originally described by Jaffe and Lichtenstein as a blowout with thin cortices.
Only one of the patients was believed to have an osteoblastoma of the spine with secondary development of an aneurysmal bone cyst, and none of the patients developed additional lesions. The patients were treated primarily with curettage and implantation of allograft chips or polymethylmethacrylate, but some patients were treated with insertion of autografts or allografts. The local recurrence rate was 20%, which is consistent with that reported by other centers.
Aneurysmal bone cysts are enigmatic lesions of unknown cause and presentation and are difficult to distinguish from other lesions. Overall, the treatment is satisfactory, but it is possible that newer approaches, such as improved magnetic resonance imaging studies, may help diagnose the lesions and allow the physicians to plan for more effective treatment protocols.
我们回顾了过去20年中治疗的一系列150例动脉瘤样骨囊肿。
病变主要位于胫骨、股骨、骨盆、肱骨和脊柱，在大多数情况下，呈现出贾菲和利希滕斯坦最初描述的具有薄皮质的爆裂样影像学表现。
仅1例患者被认为患有脊柱骨母细胞瘤并继发动脉瘤样骨囊肿，且无患者出现额外病变。患者主要接受刮除术并植入同种异体骨碎片或聚甲基丙烯酸甲酯，但部分患者接受了自体骨或异体骨植入。局部复发率为20%，与其他中心报告的一致。
动脉瘤样骨囊肿是病因和表现不明的神秘病变，难以与其他病变区分。总体而言，治疗效果令人满意，但诸如改进的磁共振成像研究等新方法可能有助于诊断病变，并使医生能够制定更有效的治疗方案。
