Wieneke Heinrich, Neumann Till, Breuckmann Frank, Hunold Peter, Fries Jochen W U, Dirsch Olaf, Erbel Raimund
Westdeutsches Herzzentrum, Klinik für Kardiologie, Universitätsklinikum, Essen.
Herz. 2005 Sep;30(6):571-4. doi: 10.1007/s00059-005-2734-1.
Isolated non-compaction of the ventricular myocardium (INVM), also known as left ventricular hypertrabeculation or spongy myocardium, belongs to the "unclassified" cardiomyopathies according to the World Health Organization. The main characteristic of this entity is a prominent trabeculation of the left ventricle with deep intertrabecular recesses communicating with the ventricular cavity. The pathomechanism of INVM is thought to be an arrest in cardiac myogenesis with persistence of embryonic myocardial morphology. The most frequent clinical manifestations include congestive heart failure, ventricular arrhythmias and systemic thromboembolic events. The therapy of INVM comprises standard medical therapy for heart failure.
孤立性心室心肌致密化不全（INVM），也称为左心室肌小梁增多或海绵状心肌，根据世界卫生组织的分类属于“未分类”心肌病。该疾病的主要特征是左心室肌小梁显著增多，肌小梁间有与心室腔相通的深陷凹。INVM的发病机制被认为是心肌生成停滞，胚胎期心肌形态持续存在。最常见的临床表现包括充血性心力衰竭、室性心律失常和全身性血栓栓塞事件。INVM的治疗包括心力衰竭的标准药物治疗。
