Evans Mark I, Ciorica Doina, Britt David W, Fletcher John C
Comprehensive Genetics, Mt. Sinai School of Medicine, New York, NY 10021, USA.
Prenat Diagn. 2005 Sep;25(9):807-13. doi: 10.1002/pd.1261.
Over the past 25 years fetal reduction has been utilized to reduce the risks of higher-order multiple pregnancies that have resulted from overly successful infertility therapies. The demographics of multiple pregnancy patients have evolved over the past decade, with increasing proportions coming from IVF as opposed to ovulation induction, being older and a higher proportion with donor eggs. Genetic diagnosis prior to reduction is becoming more common and is very safe in experienced hands. For all starting numbers, including twins, reduction to a lower number of fetuses reduces fetal losses, prematurity, and infant mortality and morbidity.
在过去25年里，减胎术已被用于降低因不孕治疗过度成功而导致的多胎妊娠风险。在过去十年中，多胎妊娠患者的人口统计学特征发生了变化，来自体外受精（IVF）的患者比例增加，而非促排卵治疗，患者年龄更大，使用供体卵子的比例更高。减胎术前的基因诊断越来越普遍，在经验丰富的医生操作下非常安全。对于所有起始胎儿数量，包括双胞胎，将胎儿数量减至更少可降低胎儿丢失、早产以及婴儿死亡率和发病率。
