D'Havé Helga, Covaci Adrian, Scheirs Jan, Schepens Paul, Verhagen Ron, De Coen Wim
Ecophysiology, Biochemistry and Toxicology Group, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium.
Environ Sci Technol. 2005 Aug 15;39(16):6016-20. doi: 10.1021/es0507259.
Few data are available on brominated flame retardants (BFRs) in terrestrial mammalian wildlife. Moreover, the use of hair in nondestructive monitoring of BFRs in mammals or humans has not been investigated. In the present study, concentrations of polybrominated diphenyl ethers (PBDEs) and brominated biphenyl 153 (BB 153) were analyzed in tissues of the European hedgehog Erinaceus europaeus. Road kills and carcasses from wildlife rescue centers were used to investigate relationships between concentrations of BFRs in hair and internal tissues, BFR tissue distribution (hair, liver, kidney, muscle, and adipose tissue), and PBDE congener tissue pattern dissimilarities. Liver concentrations of PBDEs and BB 153 were in the ranges 1-1178 and 0-2.5 ng/g of liver wet weight, respectively. PBDEs were predominant in adipose tissue and liver, while accumulation of BB 153 was tissue independent. The less persistent compound BDE 99 was more dominant in hair than in internal tissues. We observed positive relationships between BFR levels in hair and internal tissues for sum PBDEs and BDE 47 (0.37 < r < 0.78). The present study demonstrated that hair is a suitable indicator of PBDE exposure in terrestrial mammals which can be used in nondestructive monitoring schemes.
关于陆生哺乳动物体内溴化阻燃剂（BFRs）的数据很少。此外，尚未研究将毛发用于对哺乳动物或人类体内BFRs进行无损监测的情况。在本研究中，分析了欧洲刺猬（Erinaceus europaeus）组织中多溴二苯醚（PBDEs）和溴化联苯153（BB 153）的浓度。利用道路死亡动物和野生动物救援中心的尸体来研究毛发和内部组织中BFRs浓度之间的关系、BFRs的组织分布（毛发、肝脏、肾脏、肌肉和脂肪组织）以及PBDE同系物组织模式的差异。肝脏中PBDEs和BB 153的浓度分别在1 - 1178 ng/g肝脏湿重和0 - 2.5 ng/g肝脏湿重范围内。PBDEs在脂肪组织和肝脏中占主导地位，而BB 153的积累与组织无关。持久性较差的化合物BDE 99在毛发中的含量高于内部组织。我们观察到总PBDEs和BDE 47的毛发和内部组织中BFRs水平之间存在正相关关系（0.37 < r < 0.78）。本研究表明，毛发是陆生哺乳动物中PBDEs暴露的合适指标，可用于无损监测方案。
