Mendonca Derick A, Cosker Tom, Makwana Nilesh K
Department of Orthopaedics and Trauma, Wrexham Maelor Hospital, Wales, U.K.
Foot Ankle Int. 2005 Sep;26(9):761-6. doi: 10.1177/107110070502600915.
Although vacuum-assisted closure (VAC) is a well-established technique in other surgical specialties, its use has not been established in the foot and ankle. The aims of this study were to determine if vacuum-assisted closure therapy (VAC) helps assist closure in diabetic foot ulcers and wounds secondary to peripheral vascular disease, if it helps debride wounds, and if it prevents the need for further surgery.
We retrospectively reviewed 15 patients (18 wounds or ulcers) with primary diagnoses of diabetes (10 patients), chronic osteomyelitis (two patients), peripheral vascular disease (two patients), and spina bifida (one patient). Eleven of the 15 patients had serious comorbidities, such as peripheral neuropathy, renal failure, and wound dehiscence. All wounds were surgically debrided before VAC therapy was applied according to the manufacturer's instructions. The main outcome measures were time to satisfactory wound closure, changes in the wound surface area, and the need for further surgery.
Satisfactory healing was achieved in 13 of the 18 wounds or ulcers at an average of 2.5 months. VAC therapy failed in five patients (five class III ulcers), three of whom required below-knee amputations. Wound or ulcer size decreased from an average of 7.41 cm(2) before treatment to an average of 1.58 cm(2) after treatment.
VAC therapy is a useful adjunct to the standard treatment of chronic wound or ulcers in patients with diabetes or peripheral vascular disease. Its use in foot and ankle surgery leads to a quicker wound closure and, in most patients, avoids the need for further surgery.
尽管负压封闭引流(VAC)技术在其他外科专业中已得到广泛应用,但其在足踝外科的应用尚未确立。本研究的目的是确定负压封闭引流疗法(VAC)是否有助于糖尿病足溃疡和继发于周围血管疾病的伤口的闭合,是否有助于清创伤口,以及是否能避免进一步手术的需要。
我们回顾性分析了15例患者(18处伤口或溃疡),其初步诊断为糖尿病(10例)、慢性骨髓炎(2例)、周围血管疾病(2例)和脊柱裂(1例)。15例患者中有11例患有严重的合并症,如周围神经病变、肾衰竭和伤口裂开。所有伤口在按照制造商的说明应用VAC治疗之前均进行了手术清创。主要观察指标为伤口满意闭合的时间、伤口表面积的变化以及进一步手术的需求。
18处伤口或溃疡中的13处平均在2.5个月时实现了满意愈合。5例患者(5处III级溃疡)的VAC治疗失败,其中3例需要进行膝下截肢。伤口或溃疡大小从治疗前的平均7.41平方厘米降至治疗后的平均1.58平方厘米。
VAC治疗是糖尿病或周围血管疾病患者慢性伤口或溃疡标准治疗的有用辅助手段。其在足踝外科手术中的应用可使伤口更快闭合,并且在大多数患者中可避免进一步手术的需要。