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负压封闭引流(VAC)疗法在慢性糖尿病足溃疡愈合中的疗效。

Effectiveness of vacuum-assisted closure (VAC) therapy in the healing of chronic diabetic foot ulcers.

机构信息

Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

出版信息

Ann Acad Med Singap. 2010 May;39(5):353-8.

Abstract

INTRODUCTION

This is the fi rst prospective study done locally to determine the effectiveness of vacuum-assisted closure (VAC) therapy in the healing of chronic diabetic foot ulcers.

MATERIALS AND METHODS

An electronic vacuum pump was used to apply controlled negative pressure evenly across the wound surface. Changes in wound dimension, presence of wound granulation and infection status of diabetic foot ulcers in 11 consecutive patients with diabetes were followed over the course of VAC therapy.

RESULTS

Healing was achieved in all wounds. Nine wounds were closed by split-skin grafting and 2 by secondary closure. The average length of treatment with VAC therapy was 23.3 days. Ten wounds showed reduction in wound size. All wounds were satisfactorily granulated and cleared of bacterial infection at the end of VAC therapy.

CONCLUSIONS

VAC therapy was useful in the treatment of diabetic foot infection and ulcers, which after debridement, may present with exposed tendon, fascia and/or bone. These included ray amputation wounds, wounds post-debridement for necrotising fasciitis, wounds post-drainage for abscess, a heel ulcer and a sole ulcer. It was able to prepare ulcers well for closure via split-skin grafting or secondary closure in good time. This reduced cost of VAC therapy, as therapy was not prolonged to attain greater reduction in wound area. VAC therapy also provides a sterile, more controlled resting environment to large, exudating wound surfaces. Large diabetic foot ulcers were thus made more manageable.

摘要

引言

这是本地进行的首项前瞻性研究,旨在确定真空辅助闭合(VAC)疗法在治疗慢性糖尿病足溃疡方面的有效性。

材料与方法

使用电子真空泵在伤口表面均匀施加受控的负压。在 VAC 治疗过程中,连续 11 例糖尿病患者的伤口尺寸变化、伤口肉芽形成情况和糖尿病足溃疡的感染状况进行了跟踪。

结果

所有伤口均愈合。9 个伤口通过皮片移植闭合,2 个通过二期缝合闭合。VAC 治疗的平均治疗时间为 23.3 天。10 个伤口的伤口面积缩小。所有伤口在 VAC 治疗结束时均得到充分肉芽化并清除细菌感染。

结论

VAC 治疗在治疗糖尿病足感染和溃疡方面非常有用,这些溃疡在清创后可能会露出肌腱、筋膜和/或骨头。其中包括趾截肢伤口、坏死性筋膜炎清创后的伤口、脓肿引流后的伤口、足跟溃疡和足底溃疡。它能够通过皮片移植或二期缝合及时为伤口准备好良好的闭合条件。这降低了 VAC 治疗的成本,因为治疗不会延长以实现更大的伤口面积减少。VAC 治疗还为渗出性大伤口表面提供了无菌、更受控的休息环境。从而使大的糖尿病足溃疡更易于管理。

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