骨髓结节病引起的复发性严重高钙血症。

Recurrent severe hypercalcemia caused by bone marrow sarcoidosis.

作者信息

Saliba Walid R, Elias Mazen S

机构信息

Department of Medicine C, Hae'meK Medical Center, Technion-Israel Institute of Technology, Faculty of Medicine, Afula, Israel.

出版信息

Am J Med Sci. 2005 Sep;330(3):147-9. doi: 10.1097/00000441-200509000-00010.

DOI:10.1097/00000441-200509000-00010

PMID:16175000

Abstract

A 71-year-old woman with recurrent severe hypercalcemia was found to have multiple noncaseating granulomas in the bone marrow with low parathyroid hormone levels and high levels of [1,25 dihydroxycholecalciferol] that later decreased to normal levels with the normalization of calcium levels. No organ involvement other than of the bone marrow was detected, and the angiotensin-converting enzyme level was elevated. The diagnosis of bone marrow sarcoidosis is suggested.

摘要

一名71岁复发性严重高钙血症女性患者，骨髓中发现多个非干酪样肉芽肿，甲状旁腺激素水平低，[1,25-二羟胆钙化醇]水平高，随着血钙水平恢复正常，该激素水平后来也降至正常。除骨髓外未检测到其他器官受累，血管紧张素转换酶水平升高。提示诊断为骨髓结节病。