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择期与破裂腹主动脉瘤修复:1年成本效益分析。

Elective versus ruptured abdominal aortic aneurysm repair: a 1-year cost-effectiveness analysis.

作者信息

Cota A M, Omer A A, Jaipersad A S, Wilson N V

机构信息

Department of Surgery, Peterborough Hospital, Peterborough, UK.

出版信息

Ann Vasc Surg. 2005 Nov;19(6):858-61. doi: 10.1007/s10016-005-7457-5.

Abstract

Abdominal aortic aneurysm (AAA) is a life-threatening condition with an overall mortality of 80%. It predominantly affects men 65-74 years of age and is caused by focal distension of the main blood vessel in the abdomen. Most patients go undetected until their aneurysm ruptures. Controversy surrounds the most appropriate form of screening for AAA. Currently, screening is only carried out selectively in patients with peripheral vascular disease. Some patients have their AAA detected incidentally, whilst ultrasound examination of the abdomen is carried out for other indications. These patients have the opportunity to undergo surveillance or elective surgery. The mortality rate of emergency surgical intervention following rupture (50%) is far worse in comparison to that of patients undergoing planned intervention under specialist vascular surgeons (5%). Despite improvements in outcomes from elective intervention for AAA as a result of specialisation, the overall mortality from this condition remains very high (80%) as the commonest presentation of an AAA is rupture. Screening all men aged 65-74 years is considered too costly in the current economic climate. However the cost difference between elective repair and emergency repair of AAA must be considered given that the outcome from elective AAA repair is far superior to that following ruptured AAA repair. Our objective was to retrospectively collect costs and outcomes of elective and emergency AAA repair in order to carry out a cost-effectiveness analysis. Four multiprofessional teams in accident and emergency, operation theatres, intensive care, and surgical wards at the Kent and Canterbury Hospital were selected from health-care professionals including doctors, managers, nurses, and clerical staff with the purpose of obtaining costs. Detailed cost data collection sheets were prepared to calculate costs, which included staff costs, consumables including drugs, intravenous fluids, equipment, investigations, laundry, catering, and stationery. An inventory of costs per item was obtained, and the total cost was calculated from the number of items used. Outcomes were measured in terms of survival. The total costs of emergency AAA repair were pounds sterling 96,700.69, with a cost per life saved of pounds sterling 24,175.17. The total cost of elective AAA repair was pounds sterling 76,583.22, with a cost per life saved of pounds sterling 5,470.23. Emergency intervention for AAA was found to cost five times more than a planned intervention per life saved per year.

摘要

腹主动脉瘤(AAA)是一种危及生命的疾病,总体死亡率为80%。它主要影响65至74岁的男性,由腹部主要血管的局灶性扩张引起。大多数患者在动脉瘤破裂之前未被发现。对于AAA最合适的筛查形式存在争议。目前,仅对外周血管疾病患者进行选择性筛查。一些患者的AAA是在因其他指征进行腹部超声检查时偶然发现的。这些患者有机会接受监测或择期手术。与在专业血管外科医生指导下进行计划性干预的患者(5%)相比,破裂后进行紧急手术干预的死亡率(50%)要高得多。尽管由于专业化,AAA择期干预的结果有所改善,但由于AAA最常见的表现是破裂,这种疾病的总体死亡率仍然很高(80%)。在当前经济形势下,对所有65至74岁男性进行筛查被认为成本过高。然而,鉴于AAA择期修复的结果远优于破裂后修复的结果,必须考虑AAA择期修复和紧急修复之间的成本差异。我们的目标是回顾性收集AAA择期和紧急修复的成本及结果,以便进行成本效益分析。从肯特郡坎特伯雷医院的事故与急救、手术室、重症监护室和外科病房的四个多专业团队中挑选了包括医生、管理人员、护士和文职人员在内的医疗保健专业人员,以获取成本数据。准备了详细的成本数据收集表来计算成本,其中包括人员成本、耗材(包括药品、静脉输液、设备、检查、洗衣、餐饮和文具)。获取了每项物品的成本清单,并根据使用的物品数量计算总成本。结果以生存率来衡量。AAA紧急修复的总成本为96,700.69英镑,每挽救一条生命的成本为24,175.17英镑。AAA择期修复的总成本为76,583.22英镑,每挽救一条生命的成本为5,470.23英镑。结果发现,AAA的紧急干预每年每挽救一条生命的成本比计划性干预高出五倍。

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