Jeon Seokwoo, Malyarchuk Viktor, White Jeffrey O, Rogers John A
Department of Materials Science and Engineering, Beckman Institute, University of Illinois at Urbana/Champaign, Urbana, Illinois, USA.
Nano Lett. 2005 Jul;5(7):1351-6. doi: 10.1021/nl050606r.
This paper describes a simple technique for fabricating complex, but well defined, three-dimensional (3D) networks of nanoscale flow paths in the channels of microfluidic systems. Near field scanning optical measurements reveal the optics associated with the fabrication process and the key features that enable its application to the area of microfluidics. Confocal studies of microfluidic devices that incorporate 3D nanostructures formed using this approach show that they function as efficient passive mixing elements, particularly at low Reynolds numbers. This application and others such as separation and extraction inmicrofluidic total analysis systems or lab on a chip devices represent promising areas for 3D nanostructures of this general type.
本文描述了一种简单的技术，用于在微流体系统的通道中制造复杂但定义明确的纳米级流动路径三维（3D）网络。近场扫描光学测量揭示了与制造过程相关的光学特性以及使其能够应用于微流体领域的关键特征。对采用这种方法形成的包含3D纳米结构的微流体装置进行的共聚焦研究表明，它们可作为高效的被动混合元件，尤其是在低雷诺数情况下。这种应用以及微流体全分析系统或芯片实验室设备中的分离和萃取等其他应用，代表了这种一般类型的3D纳米结构的前景广阔的领域。
