Edmonds Harvey L
Neuromonitoring Associates, Incorporated, 3712 Plymouth Road, Louisville, Kentucky 40207, USA.
Ann N Y Acad Sci. 2005 Aug;1053:12-9. doi: 10.1196/annals.1344.002.
This study was a retrospective examination of the influence of multimodality neuromonitoring on the incidence of serious brain injury associated with a common type of adult cardiac surgery, coronary artery bypass grafting (CABG). Multichannel EEG, cerebral oximetry, and transcranial Doppler ultrasound were used to detect and correct imbalances in cerebral perfusion and oxygenation. Imbalances were detected in 59% of the cases and successfully corrected in all but 2%. In the absence of neuromonitoring, the expected incidence of serious brain injury is 6.1%. With neuromonitoring, the actual observed incidence was 3.0% (P = 0.03). The apparent improvement can be attributed primarily to a reduction in the number of nonembolic diffuse injuries.
本研究是一项回顾性检查，旨在探究多模态神经监测对与一种常见类型的成人心脏手术——冠状动脉旁路移植术（CABG）相关的严重脑损伤发生率的影响。使用多通道脑电图、脑血氧饱和度监测仪和经颅多普勒超声来检测和纠正脑灌注和氧合的失衡。在59%的病例中检测到失衡，除2%外所有病例均成功纠正。在没有神经监测的情况下，严重脑损伤的预期发生率为6.1%。有神经监测时，实际观察到的发生率为3.0%（P = 0.03）。这种明显的改善主要可归因于非栓塞性弥漫性损伤数量的减少。
