Zbuzková O, Binder T, Halaska M, Horácek M, Pavel P, Popelová J, Hadacová I
Gynekologicko-Porodnická Klinika, Praha.
Ceska Gynekol. 2005 Sep;70(5):367-9.
Pregnancy in a woman with thrombosis of heart valve prosthesis at the 25th week of gestation and fetal death during reimplantation of prosthesis with the use of extracorporeal circulation.
Case report.
Department of Gynecology and Obstetrics, 2nd Medical Faculty of Charles University, Motol Hospital, Prague.
Patient L. S., 24 years old, first pregnancy, admitted to coronary heart unit at the 25th week of gestation with a blocked heart valve prosthesis, NYHA IV, left heart failure, and pulmonary edema. There was an insufficient anticoagulation therapy during pregnancy and a thrombosis of the prosthetic heart valve was suspected from that reason. Reimplantation of a prosthetic heart valve with the use of extracorporeal circulation was indicated in spite of a possible risk for the fetus. The thrombosis was confirmed during cardio surgical operation and a change of the prosthesis was successfully performed. After the patient was converted to extracorporeal circulation, bradycardia and intrauterine fetal death occurred. With regard to the patient's coagulation and circulatory instability, further management was necessary because of fetal death--termination of pregnancy by minor caesarean section was the only alternative. Six hours later an 850 g weight dead fetus was delivered. There were no serious complications during the postoperative period.
Reimplantation of a prosthetic heart valve from vital indication was performed at the 25th week of gestation. After conversion of mother to extracorporeal circulation, fetal death occurred. The patients was released with satisfactory cardiopulmonal compensation.
一名妊娠25周的心脏瓣膜置换术后血栓形成的女性患者,在使用体外循环进行瓣膜再植入手术期间发生胎儿死亡。
病例报告。
布拉格莫托尔医院查理大学第二医学院妇产科。
患者L.S.,24岁,首次妊娠,妊娠25周时因心脏瓣膜置换术后堵塞、纽约心脏病协会(NYHA)心功能IV级、左心衰竭和肺水肿入住冠心病监护病房。孕期抗凝治疗不足,因此怀疑人工心脏瓣膜发生血栓形成。尽管对胎儿可能存在风险,但仍建议使用体外循环进行人工心脏瓣膜再植入手术。心脏外科手术中证实存在血栓形成,并成功更换了瓣膜。患者转为体外循环后,出现心动过缓和宫内胎儿死亡。鉴于患者凝血和循环不稳定,因胎儿死亡有必要采取进一步治疗措施——小剖宫产终止妊娠是唯一选择。6小时后娩出一名体重850克的死胎。术后期间无严重并发症。
在妊娠25周时因生命指征进行了人工心脏瓣膜再植入手术。母亲转为体外循环后,发生胎儿死亡。患者出院时心肺功能代偿良好。