罕见的刚果恶性疟原虫二氢叶酸还原酶等位基因。 - Suppr | 超能文献

Rare Congolese Plasmodium falciparum DHFR alleles.

作者信息

Wilson Paul E, Kazadi Walter, Alker Alisa P, Meshnick Steven R

机构信息

Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

出版信息

Mol Biochem Parasitol. 2005 Dec;144(2):227-9. doi: 10.1016/j.molbiopara.2005.08.008. Epub 2005 Sep 6.

DOI:10.1016/j.molbiopara.2005.08.008

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Rare Congolese Plasmodium falciparum DHFR alleles.罕见的刚果恶性疟原虫二氢叶酸还原酶等位基因。

Mol Biochem Parasitol. 2005 Dec;144(2):227-9. doi: 10.1016/j.molbiopara.2005.08.008. Epub 2005 Sep 6.

2

High prevalence of sulfadoxine/pyrimethamine resistance alleles in Plasmodium falciparum parasites from Bangladesh.孟加拉国恶性疟原虫中磺胺多辛/乙胺嘧啶抗性等位基因的高流行率。

Parasitol Int. 2010 Jun;59(2):178-82. doi: 10.1016/j.parint.2010.01.003. Epub 2010 Jan 22.

3

Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites.来自非洲5个地区的恶性疟原虫二氢叶酸还原酶基因的罕见、高度耐乙胺嘧啶等位基因。

J Infect Dis. 2004 Nov 15;190(10):1783-92. doi: 10.1086/425078. Epub 2004 Oct 18.

4

Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets.在引入经处理的蚊帐后，恶性疟原虫二氢叶酸还原酶基因中野生型的流行率在磺胺多辛/乙胺嘧啶高抗性地区有所增加。

Am J Trop Med Hyg. 2003 Sep;69(3):238-43.

5

Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria.恶性疟原虫二氢叶酸还原酶（dhfr）和二氢蝶酸合成酶（dhps）基因多态性与尼日利亚疟疾感染患者体内与年龄相关的磺胺多辛-乙胺嘧啶耐药性

Acta Trop. 2005 Sep;95(3):183-93. doi: 10.1016/j.actatropica.2005.06.015.

6

High prevalence of double Plasmodium falciparum dhfr mutations at codons 108 and 59 in the Sistan-Baluchistan province, Iran.伊朗锡斯坦-俾路支斯坦省恶性疟原虫二氢叶酸还原酶（dhfr）第108和59位密码子双重突变的高流行率。

J Infect Dis. 2003 Jun 1;187(11):1828-9. doi: 10.1086/375250.

7

A shared Asian origin of the triple-mutant dhfr allele in Plasmodium falciparum from sites across Africa.来自非洲各地疟原虫恶性疟原虫中三重突变二氢叶酸还原酶等位基因的共同亚洲起源。

J Infect Dis. 2007 Jul 1;196(1):165-72. doi: 10.1086/518512. Epub 2007 May 24.

8

Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda.二氢蝶酸合酶突变在乌干达单纯性疟疾单药及联合治疗中介导对磺胺多辛-乙胺嘧啶耐药性的主要作用

Am J Trop Med Hyg. 2004 Dec;71(6):758-63.

9

Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo.简短报告：刚果民主共和国与恶性疟原虫对磺胺多辛-乙胺嘧啶耐药性相关的分子标志物

Am J Trop Med Hyg. 2006 Jul;75(1):152-4.

10

Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women.在布基纳法索将周效磺胺-乙胺嘧啶作为孕妇间歇性预防治疗药物引入之前，其对恶性疟原虫的疗效及二氢叶酸还原酶（DHFR）突变的选择情况。

Am J Trop Med Hyg. 2007 Apr;76(4):608-13.

引用本文的文献

1

Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro.恶性疟原虫对乙胺嘧啶耐药的二氢叶酸还原酶在体外无酶活性受损情况。

Mol Biochem Parasitol. 2007 Jul;154(1):1-5. doi: 10.1016/j.molbiopara.2007.03.009. Epub 2007 Mar 20.