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利用糖尿病登记册对1998 - 2003年奥塔哥地区糖尿病护理情况的评估

Evaluation of diabetes care in the Otago region using a diabetes register, 1998-2003.

作者信息

Coppell Kirsten J, Anderson Karen, Williams Sheila, Manning Patrick, Mann Jim

机构信息

Edgar National Centre for Diabetes Research, Dunedin School of Medicine, University of Otago, P.O. Box 913, Dunedin, New Zealand.

出版信息

Diabetes Res Clin Pract. 2006 Mar;71(3):345-52. doi: 10.1016/j.diabres.2005.08.006. Epub 2005 Sep 23.

Abstract

AIM

To assess changes in diabetes care between 1998 and 2003 using data from the Otago Diabetes Register.

METHODS

A regional diabetes register was established in 1998 to monitor diabetes care in the Otago region, New Zealand. Cross-sectional data relating to process and outcome measures were collected annually from participating general practices, 93% of general practitioners in the region. Generalised estimating equations with robust standard errors were used to test for trends in clinical measures across the study period.

RESULTS

Process measures improved dramatically over the 6-year period. The proportion of patients prescribed ACE inhibitors and other antihypertensives increased markedly (32.3-52.4% and 13.2-27.1%, respectively) and both mean systolic and diastolic blood pressure decreased significantly (140.6-137.0 mmHg, p < 0.001 and 78.6-77.0 mmHg, p < 0.001, respectively). The proportion prescribed lipid lowering medication more than trebled (12.4-40.0%), while mean lipid levels improved significantly (total cholesterol: 5.94-5.21 mmol/l, p < 0.001, HDL-cholesterol: 1.23-1.28 mmol/l, p < 0.001 and triglycerides: 2.17-1.94 mmol/l, p < 0.001). Mean weight increased significantly, as did HbA1c in all treatment groups except type 2 diabetic patients treated with combined insulin and oral hypoglycaemic agents.

CONCLUSIONS

At a population level appreciable improvements in blood pressure and lipid control were observed, but not glycaemic control, probably due to insufficient attention to necessary lifestyle changes.

摘要

目的

利用奥塔哥糖尿病登记处的数据评估1998年至2003年期间糖尿病护理的变化情况。

方法

1998年建立了一个区域糖尿病登记处,以监测新西兰奥塔哥地区的糖尿病护理情况。每年从参与的全科诊所收集与过程和结果指标相关的横断面数据,该地区93%的全科医生参与其中。使用具有稳健标准误差的广义估计方程来检验整个研究期间临床指标的趋势。

结果

在这6年期间,过程指标有显著改善。开具血管紧张素转换酶抑制剂和其他抗高血压药物的患者比例显著增加(分别从32.3%增至52.4%和从13.2%增至27.1%),收缩压和舒张压均值均显著下降(分别从140.6 mmHg降至137.0 mmHg,p<0.001;从78.6 mmHg降至77.0 mmHg,p<0.001)。开具降脂药物的比例增加了两倍多(从12.4%增至40.0%),同时血脂水平显著改善(总胆固醇:从5.94 mmol/l降至5.21 mmol/l,p<0.001;高密度脂蛋白胆固醇:从1.23 mmol/l升至1.28 mmol/l,p<0.001;甘油三酯:从2.17 mmol/l降至1.94 mmol/l,p<0.001)。平均体重显著增加,除接受胰岛素和口服降糖药联合治疗的2型糖尿病患者外,所有治疗组的糖化血红蛋白均显著增加。

结论

在人群层面,观察到血压和血脂控制有明显改善,但血糖控制没有改善,这可能是由于对必要的生活方式改变关注不足。

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