Jung Michael E, Kim Wan-Joong
Department of Chemistry and Biochemistry, University of California, Los Angeles, 405 Hilgard Ave, Los Angeles, CA 90095, USA.
Bioorg Med Chem. 2006 Jan 1;14(1):92-7. doi: 10.1016/j.bmc.2005.07.068. Epub 2005 Sep 23.
The three dyes (two indocyanine and one benzoxazolium) useful in difference gel electrophoresis-methyl Cy5 1, propyl Cy3 2, and the benzoxazolium dye Cy2 3--and their NHS esters have been prepared by efficient routes in good overall yield from inexpensive precursors.
三种可用于差异凝胶电泳的染料(两种吲哚菁染料和一种苯并恶唑鎓染料)——甲基Cy5 1、丙基Cy3 2和苯并恶唑鎓染料Cy2 3——及其N-羟基琥珀酰亚胺酯已通过高效路线由廉价前体以良好的总收率制备而成。