一名患有胼胝体Ki-1间变性大细胞淋巴瘤儿童的异步爆发抑制。

Asynchronous burst-suppression in a child with callosal Ki-1 anaplastic large cell lymphoma.

作者信息

Hukin J, Davey A, Wong P, Hendson G, Aquino-Parsons C, Wu J, Sargent M

机构信息

Division of Neurology, British Columbia's Children's Hospital, University of British Columbia, Canada.

出版信息

Neurology. 2005 Sep 27;65(6):947-9. doi: 10.1212/01.wnl.0000176070.34107.f6.

DOI:10.1212/01.wnl.0000176070.34107.f6

PMID:16186544

Abstract

A 13-year-old girl with Ki-1 anaplastic large cell lymphoma (Ki-1ALCL) bulky deposits in the brain developed raised intracranial pressure and coma associated with asynchronous burst-suppression following standard dose cranial irradiation. Supportive care, steroids, and chemotherapy resulted in clinical improvement. Burst-suppression coma may be reversible when secondary to tumor, decrease in steroids, or radiation effects; the asynchrony localizes the lesion to cortical interconnections such as the corpus callosum.

摘要

一名13岁患有Ki-1间变性大细胞淋巴瘤（Ki-1ALCL）且脑部有大量病灶沉积的女孩，在接受标准剂量的颅脑照射后出现颅内压升高和昏迷，并伴有不同步的爆发抑制。支持性治疗、使用类固醇和化疗后临床症状有所改善。继发于肿瘤、类固醇减少或放疗效应的爆发抑制性昏迷可能是可逆的；不同步现象将病变定位在诸如胼胝体等皮质互连区域。