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室内氡与肺癌:一项病例对照研究。

Indoor radon and lung cancer: a case-control study.

作者信息

Vuković Branko, Faj Dario, Radolić Vanja, Planinić Josip

机构信息

Faculty of Education, Josip Jurai Strossmayer University of Osijek, L. Jagerova 9, 31000 Osijek, Croatia.

出版信息

Isotopes Environ Health Stud. 2005 Jun;41(2):169-76. doi: 10.1080/10256010412331314274.

Abstract

Lung-cancer risk to the general population from indoor radon remains controversial, although studies of radon exposure have established that radon decay products have been a cause of lung cancer among miners. For the case group of patients, suffering from lung cancer, and the control group distributions of the number of homes with high indoor levels of radon were compared with the log-normal distribution, the empirical frequency distribution of the control group obeyed the theoretical log-normal distribution. Using the ratio of frequencies of the case group to the control groups, or the relative frequencies, an association between the relative frequencies and indoor radon concentrations was found, and a positive correlation coefficient was obtained, thus enabling the rate of lung cancer to be estimated for certain indoor radon concentrations. The significant difference between the mean radon levels for the case sample and the control led to the conclusion that patients with lung cancer lived in homes with radon concentrations which were significantly higher than those of Osijek's inhabitants for the control sample.

摘要

尽管氡暴露研究已证实氡衰变产物是矿工患肺癌的一个原因,但室内氡对普通人群的肺癌风险仍存在争议。对于肺癌患者病例组,将室内氡水平高的家庭数量分布与对照组进行比较,并与对数正态分布进行对照,结果发现对照组的经验频率分布符合理论对数正态分布。通过病例组与对照组频率之比,即相对频率,发现相对频率与室内氡浓度之间存在关联,并获得了正相关系数,从而能够针对特定的室内氡浓度估算肺癌发病率。病例样本和对照组的平均氡水平存在显著差异,由此得出结论:肺癌患者居住房屋中的氡浓度显著高于对照组样本中奥西耶克居民房屋中的氡浓度。

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