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用于白内障手术的球后麻醉给药:有多少药物留存?

Sub-Tenon's anesthetic administration for cataract surgery: how much stays in?

作者信息

Patton Niall, Malik Tahira Y, Aslam Tariq M

机构信息

Department of Ophthalmology, Princess Margaret Hospital, Dunfermline, Fife, United Kingdom.

出版信息

Anesth Analg. 2005 Oct;101(4):1012-1014. doi: 10.1213/01.ane.0000168448.05964.06.

Abstract

UNLABELLED

We performed a prospective, randomized trial assessing the "remaining" volume of anesthetic solution that stays within the sub-Tenon's space after administration of 2 different volumes: 3 mL and 5 mL. The remaining volume correlated with motor block (r = 0.72; P < 0.001). The volume lost through the incision as a percentage of total volume injected was similar in both groups, suggesting sub-Tenon's space is not limited to a finite injected volume less than 5 mL and may be capable of receiving larger volumes of anesthetic to improve motor block.

IMPLICATIONS

The volume of anesthetic solution remaining within sub-Tenon's space correlates with motor block. The amount of volume lost as a percentage of total administered is independent of the volume injected, suggesting sub-Tenon's space is not limited to a finite injected volume less than 5 mL and may be capable of receiving larger volumes of anesthetic to improve motor block.

摘要

未标注

我们进行了一项前瞻性随机试验,评估给予两种不同体积(3毫升和5毫升)的麻醉溶液后,留在Tenon囊下间隙内的“剩余”溶液体积。剩余体积与运动阻滞相关(r = 0.72;P < 0.001)。两组中经切口流失的体积占总注射体积的百分比相似,这表明Tenon囊下间隙不限于小于5毫升的有限注射体积,并且可能能够容纳更大体积的麻醉剂以改善运动阻滞。

启示

Tenon囊下间隙内剩余的麻醉溶液体积与运动阻滞相关。流失体积占总给药体积的百分比与注射体积无关,这表明Tenon囊下间隙不限于小于5毫升的有限注射体积,并且可能能够容纳更大体积的麻醉剂以改善运动阻滞。

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