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与肝脾γδ T细胞淋巴瘤相关的自发性脾破裂

Spontaneous splenic rupture associated with hepatosplenic gammadelta T-cell lymphoma.

作者信息

Chen Jia-Hui, Chan De-Chuan, Lee Herng-Sheng, Liu Hsiao-Dung, Hsieh Chung-Bao, Yu Jyh-Cherng, Liu Yao-Chi, Chen Cheng-Jueng

机构信息

Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

出版信息

J Formos Med Assoc. 2005 Aug;104(8):593-6.

Abstract

Spontaneous splenic rupture is an uncommon but life-threatening complication of hematologic malignancies, despite the frequent involvement of the spleen in these diseases. It has been reported in patients with acute and chronic leukemia, Hodgkin's disease, non-Hodgkin's lymphoma, and histiocytic lymphoma. A 50-year-old previously healthy man presented with acute symptoms of spontaneous splenic rupture. Emergency splenectomy with liver biopsy was performed. The clinicopathologic features suggested a hepatosplenic gammadelta T-cell lymphoma (HSgammadeltaTL). Here, we report a rare case of spontaneous splenic rupture associated with HSgammadeltaTL, unspecified in the World Health Organization classification.

摘要

自发性脾破裂是血液系统恶性肿瘤中一种罕见但危及生命的并发症,尽管在这些疾病中脾脏经常受累。它已在急性和慢性白血病、霍奇金病、非霍奇金淋巴瘤和组织细胞淋巴瘤患者中被报道。一名50岁既往健康的男性出现了自发性脾破裂的急性症状。进行了急诊脾切除术及肝脏活检。临床病理特征提示为肝脾γδT细胞淋巴瘤(HSgammadeltaTL)。在此,我们报告一例与HSgammadeltaTL相关的自发性脾破裂罕见病例,该病例在世界卫生组织分类中未明确说明。

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