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啮齿动物肾脏中肾小球和肾小管周围毛细血管有孔内皮细胞的“窗孔穹窿”

"Pored-domes" of the fenestrated endotheliocyte of the glomerular and peritubular capillaries in the rodent kidney.

作者信息

Koriyama Y, Yamada E, Watanabe I

机构信息

Department of Anatomy, Fukuoka University School of Medicine, Japan.

出版信息

J Electron Microsc (Tokyo). 1992 Feb;41(1):30-6.

PMID:1619376
Abstract

The fenestrated endotheliocyte of peritubular and glomerular capillaries in rat and mouse kidneys were observed with SEM and TEM. In the glomerular capillary, so-called "pored-domes" were found not only at the fenestrated areolae but also at the nuclear region of the endotheliocyte. At the region between filtration surface and nuclear region, they accumulated to construct a sponge-like structure. The endotheliocyte of peritubular capillary also showed small "pored-domes". The size and morphology of the pores in the "pored-domes" of glomerular and peritubular capillaries were similar to those of areolae fenestratae of the respective capillary. Based on the findings, we assumed that pored-domes and the sponge-like structure are the reservoir for the fenestrated area of the endotheliocyte to accommodate the rapid expansion of capillary lumen.

摘要

运用扫描电子显微镜(SEM)和透射电子显微镜(TEM)观察了大鼠和小鼠肾脏肾小管周围毛细血管及肾小球毛细血管的有孔内皮细胞。在肾小球毛细血管中,不仅在有孔区域,而且在内皮细胞核区域都发现了所谓的“孔状穹顶”。在滤过表面和核区域之间的区域,它们聚集形成海绵状结构。肾小管周围毛细血管的内皮细胞也显示出小的“孔状穹顶”。肾小球和肾小管周围毛细血管“孔状穹顶”中的孔隙大小和形态与各自毛细血管的窗孔相似。基于这些发现,我们推测孔状穹顶和海绵状结构是内皮细胞有孔区域的储存库,以适应毛细血管腔的快速扩张。

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