利福布汀在利福平毒性病例中的应用

[Use of rifabutin in cases of toxicity to rifampicin].

作者信息

Moreno González B, Rodríguez Blanco A, Rodríguez Barrientos R, Vidal Pérez J L, Noguerado Asensio A

机构信息

Medicina Familiar y Salud Comunitaria Area 5, Madrid.

出版信息

Rev Clin Esp. 2005 Sep;205(9):430-2. doi: 10.1157/13079071.

DOI:10.1157/13079071

PMID:16194477

Abstract

Rifampicin is an essential drug in the present treatment of tuberculosis. On some occasions, it cannot be used due to severe adverse effects. Rifabutin is a drug of the same family, with a similar activity and difference adverse effects. This study describes the beneficial results of the substitution of rifampicin with rifabutin in patients with severe toxicity.

摘要

利福平是目前治疗结核病的一种基本药物。在某些情况下，由于严重的不良反应，它不能被使用。利福布汀是同一家族的药物，具有相似的活性和不同的不良反应。本研究描述了在严重毒性患者中用利福布汀替代利福平的有益结果。