Wan Muhaizan W M, Swaminathan M, Daud M S
Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Malays J Pathol. 2004 Jun;26(1):59-63.
Cardiac sarcoidosis is a disease of young adults. In most cases it presents with sudden death, arrhythmias, conduction disorders, heart failure or cardiomyopathy. The authors describe two cases of myocardial involvement by sarcoidosis that lead to death of the patients. Case one was a 26-year-old Indian man who was previously well and presented with sudden death. Autopsy showed nodules of sarcoid granuloma involving the heart, lungs and lymph nodes. Case two was a 47-year-old Indian lady who complained of reduced effort tolerance. Echocardiography showed that she had restrictive hypertrophic cardiomyopathy with heart failure. Seven months after initial presentation, she developed worsening of heart failure and died. Autopsy revealed involvement of the heart, lungs and liver by sarcoidosis.
心脏结节病是一种好发于年轻人的疾病。在大多数情况下，其表现为猝死、心律失常、传导障碍、心力衰竭或心肌病。作者描述了两例因结节病累及心肌导致患者死亡的病例。病例一是一名26岁的印度男性，此前身体健康，却突然死亡。尸检显示心脏、肺和淋巴结有结节病肉芽肿结节。病例二是一名47岁的印度女性，主诉运动耐量下降。超声心动图显示她患有限制性肥厚型心肌病并伴有心力衰竭。初次就诊七个月后，她的心力衰竭病情恶化并死亡。尸检显示心脏、肺和肝脏均有结节病累及。
