Blennow Kaj, Popa Cornel, Rasulzada Abdullah, Minthon Lennart, Wallin Anders, Zetterberg Henrik
Institutionen för klinisk neurovetenskap, Sahlgrenska Universitetssjukhuset/Mölndal, Sweden.
Lakartidningen. 2005;102(36):2468-70, 2472-5.
The clinical symptomatology and pathogenic mechanisms of chronic traumatic brain injury associated with boxing (CTBI-B) is reviewed. This syndrome is also known as punch drunk syndrome or dementia pugilistica. Since even milder forms of CTBI-B are rare among amateur boxers, we make a distinction between amateur and professional boxing throughout the review. Focus is also set on the interesting similarities in neurochemical changes and pathogenic mechanisms between CTBI-B, acute traumatic brain injury (e.g. road traffic accidents) and Alzheimer's disease.
本文综述了与拳击相关的慢性创伤性脑损伤（CTBI-B）的临床症状学和致病机制。该综合征也被称为拳击醉酒综合征或拳击性痴呆。由于即使是较轻形式的CTBI-B在业余拳击手中也很少见，因此在整个综述中我们区分了业余拳击和职业拳击。同时还重点关注了CTBI-B、急性创伤性脑损伤（如道路交通事故）和阿尔茨海默病在神经化学变化和致病机制方面有趣的相似之处。
