Oyama H, Nagane M, Shibui S, Nomura K, Mukai K
Department of Neurosurgery, National Cancer Center Hospital, Tokyo.
Jpn J Clin Oncol. 1992 Apr;22(2):131-5.
A case of primary malignant lymphoma of the skull base is reported. A 62-year-old man was admitted with headache and diplopia. Computed tomography and magnetic resonance imaging showed an abnormal mass in the right parasellar region. The final diagnosis after surgery was primary malignant lymphoma of the skull base. Primary malignant lymphomas sometimes occur in the central nervous system but those in the skull base are exceptional. The present paper presents just such a rare case of malignant lymphoma of the skull base. Diagnosis and combined therapy consisting of surgery, radiotherapy and chemotherapy for the disease are discussed, and the literature on recent clinical problems of central nervous system lymphomas is reviewed.
报告了1例原发性颅底恶性淋巴瘤。一名62岁男性因头痛和复视而入院。计算机断层扫描和磁共振成像显示右鞍旁区域有异常肿块。手术后的最终诊断为原发性颅底恶性淋巴瘤。原发性淋巴瘤有时发生于中枢神经系统,但发生于颅底者较为罕见。本文报道了这样1例罕见的颅底恶性淋巴瘤病例。文中讨论了该病的诊断以及手术、放疗和化疗的联合治疗方法,并综述了有关中枢神经系统淋巴瘤近期临床问题的文献。