Akiba T, Naruke T, Kondo H, Goya T, Tsuchiya R, Suemasu K, Noguchi M, Sakurai K
First Department of Surgery, Jikei University School of Medicine, Tokyo.
Jpn J Clin Oncol. 1992 Apr;22(2):92-5.
A retrospective study was conducted on 32 patients who had had bronchial carcinoid tumors between 1965 and 1989. The average age of the patients was 48.5 years, with a male to female ratio of 3.6:1. Of the 32 patients, 28 were diagnosed pathologically to have typical bronchial carcinoid tumors and the other four, atypical bronchial carcinoid tumors. Twenty-two of the 28 typical bronchial carcinoid tumors were classified as stage I, but only one of the four atypical bronchial carcinoid tumors was at stage I. Two typical carcinoid tumor patients and two atypical carcinoid tumor patients were found, pathologically, to have lymph node metastasis. The typical carcinoid tumors showed a more significant endobronchial polypoid growth than the atypical carcinoid tumors (P = 0.0138). The five-year-survival rate was 100% in patients with typical carcinoid tumors and 25% in those with atypical carcinoid tumors. The difference between the five-year-survival rate for the typical carcinoid and atypical carcinoid patients was statistically significant (P = 0.001).
对1965年至1989年间患有支气管类癌肿瘤的32例患者进行了一项回顾性研究。患者的平均年龄为48.5岁,男女比例为3.6:1。在这32例患者中,28例经病理诊断为典型支气管类癌肿瘤,另外4例为非典型支气管类癌肿瘤。28例典型支气管类癌肿瘤中有22例被归类为I期,但4例非典型支气管类癌肿瘤中只有1例处于I期。经病理检查发现,2例典型类癌肿瘤患者和2例非典型类癌肿瘤患者有淋巴结转移。典型类癌肿瘤比非典型类癌肿瘤表现出更显著的支气管内息肉样生长(P = 0.0138)。典型类癌肿瘤患者的五年生存率为100%,非典型类癌肿瘤患者为25%。典型类癌肿瘤和非典型类癌肿瘤患者的五年生存率差异具有统计学意义(P = 0.001)。