Huwer H, Kalweit G, Krüger B, Straub U, Schäfers H J
Abteilung für Thorax- und Herz-Gefässchirurgie der Universität des Saarlandes, Homburg.
Pneumologie. 1996 Nov;50(11):786-9.
From 1976 to 1996 sixty patients with bronchopulmonary carcinoid were operated on at our institution. Post-operative histologic examination revealed typical carcinoid tumors in 50 cases and atypical carcinoid tumors in 10 cases. Preoperative diagnosis was correct in 32 cases (53%) and wrong in 11 cases (18%). In 17 cases (29%) we carried out a diagnostic thoracotomy. Resection was potentially for cure in 55/60 patients. Five-year-survival rates were 100% for patients with typical carcinoid tumors and 97% and 92% at 10 and 15 years, respectively. Regional lymphatic tissue was involved in typical (12%) as well as in atypical carcinoid tumors (20%). Furthermore distant metastasis occurred in both types of tumors, 4% in typical and 11% in atypical carcinoid tumors. There was no relationship between lymph node involvement and distant metastasis. Local recurrence was seen in 2/60 patients. Both patients suffered from atypical carcinoid tumors. Patients in whom only incomplete resection due to advanced tumor stage was possible showed no benefit from operative therapy.
1976年至1996年，我院对60例支气管肺类癌患者进行了手术。术后组织学检查显示，50例为典型类癌肿瘤，10例为非典型类癌肿瘤。术前诊断正确32例（53%），错误11例（18%）。17例（29%）患者进行了诊断性开胸手术。60例患者中有55例有可能通过切除达到治愈。典型类癌肿瘤患者的5年生存率为100%，10年和15年生存率分别为97%和92%。典型类癌肿瘤（12%）和非典型类癌肿瘤（20%）均有区域淋巴组织受累。此外，两种类型的肿瘤均发生远处转移，典型类癌肿瘤为4%，非典型类癌肿瘤为11%。淋巴结受累与远处转移之间无相关性。60例患者中有2例出现局部复发。这两名患者均患有非典型类癌肿瘤。因肿瘤分期较晚仅行不完全切除的患者未从手术治疗中获益。
