Calretas Susana, Leitão Sara, Cortesão Emília, Espadana Ana Isabel, Santos Rui M, Porto Armando
Serviço de Medicina III, Hospitais da Universidade de Coimbra.
Acta Med Port. 2004 Sep-Oct;17(5):405-8. Epub 2004 Dec 20.
Central diabetes insipidus, is a syndrome characterized by the excretion of abnormally elevated volumes of diluted urine, due to the diminution of reabsorption of water in the collecting ducts, induced by the diminution of production of antidiuretic hormone. The involvement of the central nervous system in the leukaemia is frequent, but the association leukaemia/diabetes insipidus is rare. We describe a clinical case of a 40 years old female, whose first manifestation of leukaemia was diabetes insipidus; we discuss the difficulties of diagnosis, the particularities of the case and its evolution.
中枢性尿崩症是一种综合征，其特征是由于抗利尿激素分泌减少导致集合管对水的重吸收减少，从而排出异常大量的稀释尿液。白血病累及中枢神经系统很常见，但白血病/尿崩症的关联很少见。我们描述了一名40岁女性的临床病例，其白血病的首发表现为尿崩症；我们讨论了诊断的困难、该病例的特殊性及其病情发展。
