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1
Nonelectrophoretic genetic variability in mosquitoes: polymorphism for temperature-resistant and temperature-sensitive phosphoglucomutase alleles in Culex pipiens.蚊子的非电泳遗传变异性：致倦库蚊中耐温和热敏磷酸葡萄糖变位酶等位基因的多态性
Genetics. 1979 Sep;93(1):201-9. doi: 10.1093/genetics/93.1.201.
2
A simple approach for discovering common nonelectrophoretic enzyme variability: a heat denaturation study in Drosophila melanogaster.一种发现常见非电泳酶变异性的简单方法：黑腹果蝇的热变性研究。
Biochem Genet. 1978 Apr;16(3-4):299-305. doi: 10.1007/BF00484086.
3
Electrophoretic and heat-stability polymorphism at the phosphoglucomutase (Pgm) locus in natural populations of Drosophila melanogaster.黑腹果蝇自然种群中磷酸葡萄糖变位酶（Pgm）位点的电泳和热稳定性多态性。
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4
Dynamics of phosphoglucomutase heat sensitivity polymorphism in Culicidae.
Experientia. 1980 Feb 15;36(2):174-6. doi: 10.1007/BF01953715.
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Investigations on the PGM (phosphoglucomutase) polymorphism by isoelectric focusing in Drosophila melanogaster.通过等电聚焦对黑腹果蝇中磷酸葡萄糖变位酶（PGM）多态性的研究。
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Further genetic heterogeneity of human red cell phosphoglucomutase-1: a mon-electrophoretic polymorphism.人类红细胞磷酸葡萄糖变位酶-1的进一步遗传异质性：一种单电泳多态性。
Ann Hum Genet. 1981 Oct;45(4):313-22. doi: 10.1111/j.1469-1809.1981.tb00344.x.
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Temporal and geographic genetic variation in Culex pipiens quinquefasciatus (Diptera: Culicidae) from Florida.来自佛罗里达州的致倦库蚊（双翅目：蚊科）的时间和地理遗传变异
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Phosphoglucomutase polymorphism in the oriental fruit fly, Dacus dorsalis (Diptera, Tephritidae) from Peninsular Malaysia.马来西亚半岛东方果实蝇（Dacus dorsalis，双翅目，实蝇科）中的磷酸葡萄糖变位酶多态性
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引用本文的文献

1
Investigations on the PGM (phosphoglucomutase) polymorphism by isoelectric focusing in Drosophila melanogaster.通过等电聚焦对黑腹果蝇中磷酸葡萄糖变位酶（PGM）多态性的研究。
Biochem Genet. 1990 Jun;28(5-6):247-55. doi: 10.1007/BF02401415.

本文引用的文献

1
Genic Heterogeneity at Two Alcohol Dehydrogenase Loci in DROSOPHILA PSEUDOOBSCURA and DROSOPHILA PERSIMILIS.两个酒精脱氢酶基因座在黑腹果蝇和拟暗果蝇中的遗传异质性。
Genetics. 1977 Oct;87(2):285-304. doi: 10.1093/genetics/87.2.285.
2
PHOSPHOGLUCOMUTASE POLYMORPHISM IN MAN.人类中的磷酸葡萄糖变位酶多态性
Nature. 1964 Nov 21;204:742-5. doi: 10.1038/204742a0.
3
Isoallele frequencies in very large populations.非常大的群体中的等基因频率。
Genetics. 1974 Mar;76(3):607-13. doi: 10.1093/genetics/76.3.607.
4
Heat stability variants of esterase-6 in Drosophila melanogaster.
Nature. 1976 Sep 9;263(5573):131-2. doi: 10.1038/263131a0.
5
Further evidence of thermostability variation within electrophoretic mobility classes of enzymes.酶电泳迁移率类别内热稳定性变化的进一步证据。
Biochem Genet. 1976 Apr;14(3-4):383-7. doi: 10.1007/BF00484776.
6
Isolation and genetic characterization of alcohol dehydrogenase thermostability variants occurring in natural populations of Drosophila melanogaster.黑腹果蝇自然种群中出现的乙醇脱氢酶热稳定性变异体的分离与遗传特征分析
Biochem Genet. 1977 Oct;15(9-10):971-88. doi: 10.1007/BF00483992.
7
A simple approach for discovering common nonelectrophoretic enzyme variability: a heat denaturation study in Drosophila melanogaster.一种发现常见非电泳酶变异性的简单方法：黑腹果蝇的热变性研究。
Biochem Genet. 1978 Apr;16(3-4):299-305. doi: 10.1007/BF00484086.
8
Hidden phosphoglucomutase (PGM) genetic polymorphism in a natural population of Culiseta litorea (Diptera, Culicidae).
Parassitologia. 1977 Jan-Aug;19(1-2):103-7.

蚊子的非电泳遗传变异性：致倦库蚊中耐温和热敏磷酸葡萄糖变位酶等位基因的多态性

Nonelectrophoretic genetic variability in mosquitoes: polymorphism for temperature-resistant and temperature-sensitive phosphoglucomutase alleles in Culex pipiens.

作者信息

Scozzari R, Trippa G, Petrarca V, Cicchetti R

出版信息

Genetics. 1979 Sep;93(1):201-9. doi: 10.1093/genetics/93.1.201.

DOI:10.1093/genetics/93.1.201
PMID:161979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1217827/
Abstract

Homogenates of single individuals of two natural populations and five laboratory populations of Culex pipiens were examined by combining electrophoresis and heat denaturation studies on phosphoglucomutase (PGM). All populations showed a high degree of polymorphism for isoelectrophoretic temperature-resistant (tr) and temperature-sensitive (ts) alleles. Formal genetic data on the heat stability differences of the PGM are given. If both electrophoretic and isoelectrophoretic alleles are taken into account, the mean increase in the degree of heterozygosity is quite remarkable, i.e., about 65%.--The data are considered in relation to the biological significance that this new type of variability of structural genes could have in natural populations.

摘要

通过结合磷酸葡萄糖变位酶（PGM）的电泳和热变性研究，对淡色库蚊两个自然种群和五个实验室种群的单个个体匀浆进行了检测。所有种群在等电泳耐热（tr）和温度敏感（ts）等位基因方面均表现出高度多态性。给出了关于PGM热稳定性差异的正式遗传数据。如果同时考虑电泳等位基因和等电泳等位基因，杂合度的平均增加相当显著，即约65%。——这些数据与这种结构基因新型变异性在自然种群中可能具有的生物学意义相关联进行了考量。