Carrafiello Gianpaolo, Laganà Domenico, Mangini Monica, Cuffari Salvatore, Cafaro Tamara, Recaldini Chiara, Genovese Eugenio, Fugazzola Carlo
Università degli Studi dell'Insubria, Varese.
Radiol Med. 2005 Sep;110(3):249-61.
To evaluate the role and the effectiveness of interventional radiology in the treatment of renal transplant complications.
From 1996 to 2004 a total of 288 kidney transplants from cadavers were performed in our Institute. The kidney was always collocated in iliac fossa by creating a vascular anastomosis with the external iliac artery and vein; in all cases the ureter was implanted into the recipient bladder. During the follow-up, 34 complications were observed. Twenty-seven complications in 25 patients (20 males and 5 females; age 35-65 years) were treated by a radiologic procedure: 9 renal artery stenosis and 1 native external iliac artery stenosis (by PTA), 5 ureteral obstructions (by nephrostomy and ureteral stenting), 8 ureteral leaks (by nephrostomy, in 2 cases associated to ureteral stenting) and 4 limphoceles (by percutaneous ultrasound-guided catheter drainage).
Primary technical success was obtained in 20/27 cases (74%). Success was obtained with a second interventional procedure in 3/27 cases, 2 limphoceles and 1 ureteral fistula (secondary technical success: 85.2%), with a clinical final success in 23/27 cases (85.2%). We observed a peri-procedural complication rate of 3.7% (1 renal artery post-PTA dissection during a restenosis treatment). Four cases (1 renal arterial post-PTA dissection, 1 ureteral obstruction, 1 ureteral leak and 1 limphocele) needed a surgical correction (14.8%).
Interventional radiology is the first therapeutic approach to treat renal transplant complications. It shows good technical and clinical results and a low complication rate. Surgery had to be considered only if minimally invasive procedures are infeasible or ineffective.
评估介入放射学在肾移植并发症治疗中的作用及效果。
1996年至2004年,我院共进行了288例尸体肾移植手术。通过将肾与髂外动脉和静脉进行血管吻合,肾脏总是置于髂窝;所有病例中,输尿管均植入受者膀胱。随访期间,观察到34例并发症。25例患者(20例男性,5例女性;年龄35 - 65岁)出现的27例并发症采用放射学方法治疗:9例肾动脉狭窄和1例髂外动脉狭窄(通过经皮腔内血管成形术),5例输尿管梗阻(通过肾造瘘术和输尿管支架置入术),8例输尿管漏(通过肾造瘘术,2例伴有输尿管支架置入术)和4例淋巴囊肿(通过经皮超声引导下导管引流)。
27例中有20例(74%)获得了初次技术成功。27例中有3例通过第二次介入手术获得成功,2例淋巴囊肿和1例输尿管瘘(二次技术成功率:85.2%),27例中有23例获得临床最终成功(85.2%)。我们观察到围手术期并发症发生率为3.7%(1例在再狭窄治疗期间肾动脉经皮腔内血管成形术后夹层形成)。4例(1例肾动脉经皮腔内血管成形术后夹层形成、1例输尿管梗阻、1例输尿管漏和1例淋巴囊肿)需要手术矫正(14.8%)。
介入放射学是治疗肾移植并发症的首选治疗方法。它显示出良好的技术和临床效果以及较低的并发症发生率。仅在微创操作不可行或无效时才考虑手术治疗。