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介入放射学在肾移植并发症管理中的作用。

The role of interventional radiology in the management of kidney transplant complications.

作者信息

Carrafiello Gianpaolo, Laganà Domenico, Mangini Monica, Cuffari Salvatore, Cafaro Tamara, Recaldini Chiara, Genovese Eugenio, Fugazzola Carlo

机构信息

Università degli Studi dell'Insubria, Varese.

出版信息

Radiol Med. 2005 Sep;110(3):249-61.

Abstract

PURPOSE

To evaluate the role and the effectiveness of interventional radiology in the treatment of renal transplant complications.

MATERIALS AND METHODS

From 1996 to 2004 a total of 288 kidney transplants from cadavers were performed in our Institute. The kidney was always collocated in iliac fossa by creating a vascular anastomosis with the external iliac artery and vein; in all cases the ureter was implanted into the recipient bladder. During the follow-up, 34 complications were observed. Twenty-seven complications in 25 patients (20 males and 5 females; age 35-65 years) were treated by a radiologic procedure: 9 renal artery stenosis and 1 native external iliac artery stenosis (by PTA), 5 ureteral obstructions (by nephrostomy and ureteral stenting), 8 ureteral leaks (by nephrostomy, in 2 cases associated to ureteral stenting) and 4 limphoceles (by percutaneous ultrasound-guided catheter drainage).

RESULTS

Primary technical success was obtained in 20/27 cases (74%). Success was obtained with a second interventional procedure in 3/27 cases, 2 limphoceles and 1 ureteral fistula (secondary technical success: 85.2%), with a clinical final success in 23/27 cases (85.2%). We observed a peri-procedural complication rate of 3.7% (1 renal artery post-PTA dissection during a restenosis treatment). Four cases (1 renal arterial post-PTA dissection, 1 ureteral obstruction, 1 ureteral leak and 1 limphocele) needed a surgical correction (14.8%).

CONCLUSIONS

Interventional radiology is the first therapeutic approach to treat renal transplant complications. It shows good technical and clinical results and a low complication rate. Surgery had to be considered only if minimally invasive procedures are infeasible or ineffective.

摘要

目的

评估介入放射学在肾移植并发症治疗中的作用及效果。

材料与方法

1996年至2004年,我院共进行了288例尸体肾移植手术。通过将肾与髂外动脉和静脉进行血管吻合,肾脏总是置于髂窝;所有病例中,输尿管均植入受者膀胱。随访期间,观察到34例并发症。25例患者(20例男性,5例女性;年龄35 - 65岁)出现的27例并发症采用放射学方法治疗:9例肾动脉狭窄和1例髂外动脉狭窄(通过经皮腔内血管成形术),5例输尿管梗阻(通过肾造瘘术和输尿管支架置入术),8例输尿管漏(通过肾造瘘术,2例伴有输尿管支架置入术)和4例淋巴囊肿(通过经皮超声引导下导管引流)。

结果

27例中有20例(74%)获得了初次技术成功。27例中有3例通过第二次介入手术获得成功,2例淋巴囊肿和1例输尿管瘘(二次技术成功率:85.2%),27例中有23例获得临床最终成功(85.2%)。我们观察到围手术期并发症发生率为3.7%(1例在再狭窄治疗期间肾动脉经皮腔内血管成形术后夹层形成)。4例(1例肾动脉经皮腔内血管成形术后夹层形成、1例输尿管梗阻、1例输尿管漏和1例淋巴囊肿)需要手术矫正(14.8%)。

结论

介入放射学是治疗肾移植并发症的首选治疗方法。它显示出良好的技术和临床效果以及较低的并发症发生率。仅在微创操作不可行或无效时才考虑手术治疗。

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