Tanţău Marcel, Tanţău Alina, Zaharia Teodor, Cucuianu Andrei
3rd Medical Clinic, University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Rom J Gastroenterol. 2005 Sep;14(3):273-8.
Primary gastrointestinal non-Hodgkin lymphoma accounts for 13-18% of all malignant tumours of small bowel and only 1 % of large bowel tumours (1). Multiple lymphomatous polyposis is a rare entity, characterized by the presence of multiple lymphomatous polyps along the gut (2). Majority of cases with gastrointestinal primary lymphoma are classified histologically as "mantle cell" lymphomas. A 59 year old patient was admitted to our clinic for fatigue and rectal bleeding. Endoscopic examination of the colon revealed an infiltrative-exulcerative lesion of the terminal ileon, a polypoid mass on ileocecal valve and multiple polyps over the entire colon and rectum. Gastroscopy revealed polyps into the duodenal bulb. Histopathological and immunohistochemical studies on biopsy specimens from colon and duodenum confirmed gastrointestinal non-Hodgkin lymphoma, probably "mantle cell" lymphoma. Because she was in an advanced stage she received only cytostatic treatment. A clinical, endoscopical and histopathological follow up at 3, 6 and 12 months was performed.
原发性胃肠道非霍奇金淋巴瘤占小肠所有恶性肿瘤的13% - 18%,仅占大肠肿瘤的1%(1)。多发性淋巴瘤性息肉病是一种罕见的病症,其特征是沿肠道存在多个淋巴瘤性息肉(2)。大多数胃肠道原发性淋巴瘤病例在组织学上被分类为“套细胞”淋巴瘤。一名59岁患者因疲劳和直肠出血入住我院。结肠镜检查发现回肠末端有浸润性溃疡病变,回盲瓣有息肉样肿物,整个结肠和直肠有多个息肉。胃镜检查发现十二指肠球部有息肉。对结肠和十二指肠活检标本进行的组织病理学和免疫组织化学研究证实为胃肠道非霍奇金淋巴瘤,可能为“套细胞”淋巴瘤。由于她处于晚期,仅接受了细胞抑制治疗。在3、6和12个月时进行了临床、内镜和组织病理学随访。