Peng K, Liu L, Zhang Y, Gong S, Shao Y
Department of General Surgery, Sixth Hospital of Wuhan, Wuhan 430015, China.
Zhonghua Wai Ke Za Zhi. 2001 Dec;39(12):908-10.
To evaluate the predictive effects of the new lymph node staging system based on the ratio of the number of metastatic lymph nodes to the total number of dissected lymph nodes comparing with N-staging of the 5th TNM (UICC, 1997).
Lymph nodes harvested from operative specimens in 78 patients with gastric cancer were examined histologically. pN staging was carried out according to the two staging systems respectively. In our system, pN0, pN1, pN2, pN3 were defined as lymph node ratio(LNR) 0, <10%, <25% and >25%, respectively. All the patients were followed up and the data were analyzed statistically.
A total of 5388 lymph nodes were found with a mean of 69 per case (range 30-157). Lymph node metastases were detected in 59 patients (75.64%). The 3-year survival rates of pN0, pN1, pN2, pN3 of the new staging system were 100%, 68.42%, 7.58% and 6.78%, respectively.
The lymph node ratio is a relative variable, which reflects the degree of metastasis of lymph node, and is more predictable than the UICC 1997 5th N-staging system defined as the numbers of metastatic lymph node.
评估基于转移淋巴结数量与清扫淋巴结总数之比的新淋巴结分期系统相较于第5版TNM分期（UICC，1997）中N分期的预测效果。
对78例胃癌手术标本所取淋巴结进行组织学检查。分别依据两种分期系统进行pN分期。在我们的系统中，pN0、pN1、pN2、pN3分别定义为淋巴结比率（LNR）为0、<10%、<25%和>25%。对所有患者进行随访并对数据进行统计学分析。
共发现5388个淋巴结，平均每例69个（范围30 - 157个）。59例（75.64%）检测到淋巴结转移。新分期系统中pN0、pN1、pN2、pN3的3年生存率分别为100%、68.42%、7.58%和6.78%。
淋巴结比率是一个相对变量，它反映了淋巴结转移程度，并且比UICC 1997第5版以转移淋巴结数量定义的N分期系统更具预测性。
