介导扑翼样震颤的皮质机制。

Cortical mechanisms mediating asterixis.

作者信息

Artieda J, Muruzabal J, Larumbe R, García de Casasola C, Obeso J A

机构信息

Department of Neurology, Clinica Universitaria, University of Navarra, Pamplona, Spain.

出版信息

Mov Disord. 1992;7(3):209-16. doi: 10.1002/mds.870070304.

DOI:10.1002/mds.870070304

PMID:1620137

Abstract

We describe a patient with chronic renal failure who suffered multifocal action-induced jerks. Electromyography (EMG) recorded the typical silence of asterixis. Back-averaging the EEG activity preceding the EMG silent periods in the forearm showed a biphasic wave antedating the asterixis by 23 ms. Somatosensory evoked potentials (SEPs) after median nerve stimulation were pathologically enlarged on both hemispheres. Brain-mapping of the biphasic wave preceding asterixis and the giant SEPs indicated a common origin in the sensorimotor cortex. This observation provides further documentation of a cortical origin for some types of asterixis in humans.

摘要

我们描述了一名患有慢性肾衰竭的患者，该患者出现多灶性动作诱发性抽搐。肌电图（EMG）记录到典型的扑翼样震颤静息期。对前臂EMG静息期之前的脑电图（EEG）活动进行反向平均，结果显示在扑翼样震颤之前23毫秒出现一个双相波。正中神经刺激后的体感诱发电位（SEP）在双侧半球均出现病理性增大。对扑翼样震颤之前的双相波和巨大SEP进行脑图谱分析表明，它们起源于感觉运动皮层的同一部位。这一观察结果进一步证明了人类某些类型扑翼样震颤的皮层起源。