纽约布朗克斯县儿童哮喘住院情况与环境空气中二氧化硫浓度

Childhood asthma hospitalizations and ambient air sulfur dioxide concentrations in Bronx County, New York.

作者信息

Lin Shao, Hwang Syni-An, Pantea Cristian, Kielb Christine, Fitzgerald Edward

机构信息

Bureau of Environmental and Occupational Epidemiology, Center for Environmental Health, New York State Department of Health, Troy, New York 12180, USA.

出版信息

Arch Environ Health. 2004 May;59(5):266-75. doi: 10.3200/AEOH.59.5.266-275.

DOI:10.3200/AEOH.59.5.266-275

PMID:16201673

Abstract

The association between asthma hospitalizations and ambient sulfur dioxide (SO2) concentrations was examined in a case-control study in Bronx County, New York. Cases comprised 2629 children aged 0-14 yr who were admitted to hospitals for asthma. There were 2236 controls who were admitted for reasons other than asthma. Daily ambient SO2 concentrations were categorized into quartiles of both average and maximum levels and various exposure windows (i.e., day of admission and 1-, 2-, and 3-d lags). Cases were exposed to higher daily average concentrations of SO2 than controls. The authors compared the highest exposure quartile with the lowest, and the odds ratios were 1.66, 1.90, 2.05, and 2.21 (all p < 0.01 for same-day, 1-, 2-, and 3-d lags, respectively), with a similar finding for daily SO2 maximum exposure. The results suggest a consistent positive association between SO2 exposure and hospitalizations for childhood asthma.

摘要

在纽约布朗克斯县进行的一项病例对照研究中，对哮喘住院与环境二氧化硫（SO₂）浓度之间的关联进行了研究。病例包括2629名0至14岁因哮喘住院的儿童。有2236名对照，他们因哮喘以外的原因住院。每日环境SO₂浓度按平均水平和最高水平的四分位数以及不同的暴露窗口（即入院当天以及滞后1天、2天和3天）进行分类。病例比对照接触到更高的每日平均SO₂浓度。作者将最高暴露四分位数与最低暴露四分位数进行了比较，比值比分别为1.66、1.90、2.05和2.21（同日、滞后1天、2天和3天的p值均<0.01），每日SO₂最高暴露情况也有类似发现。结果表明，SO₂暴露与儿童哮喘住院之间存在一致的正相关。