Tabei S Z, Amin A, Mowla A, Nabavizadeh S A, Razmkon A
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
East Mediterr Health J. 2004 Jan-Mar;10(1-2):27-36.
Anthrax, like tuberculosis, shows a new epidemic spread in industrialized countries, revealing some ambiguous aspects to the disease and providing new challenges to medicine. Shiraz University of Medical Sciences has records of 7130 autopsies performed in the past 40 years, 33 of which are anthrax cases. We reviewed all the pathology slides of these cases and classified the organs involved in a search for unrecognized microscopic findings. The most common cause of death was sepsis, caused by organ involvement and direct cytotoxicity of Bacillus anthracis, in addition to its exotoxin production. Novel findings included hyaline membrane formation in respiratory system cases that is similar to acute (adult) respiratory distress syndrome and evidence of primary gastrointestinal involvement, showing the ability of the organism to pass the gastric barrier.
炭疽与结核病一样，在工业化国家呈现出新的流行趋势，这揭示了该疾病的一些模糊之处，并给医学带来了新的挑战。设拉子医科大学有过去40年里进行的7130例尸检记录，其中33例为炭疽病例。我们复查了这些病例的所有病理切片，并对受累器官进行分类，以寻找未被识别的微观发现。最常见的死亡原因是败血症，这是由炭疽杆菌的器官受累、直接细胞毒性以及其外毒素产生所致。新发现包括呼吸系统病例中出现类似于急性（成人）呼吸窘迫综合征的透明膜形成，以及原发性胃肠道受累的证据，表明该生物体有穿过胃屏障的能力。
