Belovicova M, Kinova S, Hrusovsky S
1st Department of Internal Medicine, Slovak Medical University, Bratislava, Slovakia.
Bratisl Lek Listy. 2005;106(6-7):203-6.
The differentiation of congestive heart failure from pulmonary cause of dyspnea is of extreme importance in patients presenting with acute shortness of breath. It seems that the use of B-type natriuretic peptide (BNP) can speed up the diagnostic process significantly.
79 patients (46 men - 58.2%, average 71.9, range 43-92; 33 women - 41.8%, average 75.5, range 51-93). In each of them we measured BNP concentrations by means of rapid fluorescent immunoassay.
We divided the patients according to BNP results into two groups: BNP positive and BNP negative. There were 28 BNP negative patients -35.40% (13 men, 15 women). BNP positive patients (51) were divided into NYHA I-IV groups in accordance with BNP results.
The rapid, highly sensitive and specific measurement of BNP concentrations in the patients with dyspnea can significantly help to differentiate the cardiac and pulmonary causes of dyspnea (Tab. 1, Fig. 1, Ref. 24).
对于急性呼吸急促的患者，区分充血性心力衰竭和肺部原因导致的呼吸困难极为重要。似乎使用B型利钠肽（BNP）可以显著加快诊断过程。
79例患者（46例男性，占58.2%，平均年龄71.9岁，范围43 - 92岁；33例女性，占41.8%，平均年龄75.5岁，范围51 - 93岁）。我们通过快速荧光免疫测定法测量了他们每个人的BNP浓度。
我们根据BNP结果将患者分为两组：BNP阳性组和BNP阴性组。有28例BNP阴性患者，占35.40%（13例男性，15例女性）。BNP阳性患者（51例）根据BNP结果被分为纽约心脏协会（NYHA）I - IV级组。
对呼吸困难患者进行BNP浓度的快速、高度敏感且特异的测量，可显著有助于区分呼吸困难的心脏和肺部原因（表1，图1，参考文献24）。
