Mazhar Syeda Batool
Department of Obstetrics and Gynaecology, Mother and Child Health Center, PIMS, Islamabad.
J Coll Physicians Surg Pak. 2005 Aug;15(8):476-80.
To determine fetal and maternal outcomes in women presenting with heart disease during pregnancy and labor.
Descriptive study.
Department of Gynae/Obstetrics, MCH, Center, Unit II, PIMS, Islamabad, during a period of 2 years from March 2001 to February 2003.
Forty-two pregnant women with heart disease delivered at MCH Center, Unit II, during the study period were included. Maternal outcome measures included obstetric and medical complications and maternal mortality while fetal outcome measures were prematurity, intrauterine growth restriction and perinatal mortality, intrauterine death and indicated terminations of pregnancy.
The mean age was 27.50 -/+ 5.17 years (standard deviation). Of the 42 women, 33 (78.6%) were booked for antenatal care and 9 (21.4%) were non-booked. Congenital heart disease was present in 7 (16.7%) while 28 (65.3%) had rheumatic heart disease and mitral valve disease was the commonest. Among the remaining 7 women with acquired heart disease, 3 (7.1%) women had ischemic heart diseases (IHD), 1 (2.4%) had primary pulmonary hypertension, 2 (4.8%) patients had peripartum cardiomyopathy and 1 (2.4%) had aortic dissection. Based on New York Heart Association Functional classification (NYHA) 16 (38.1%) patients were asymptomatic (class I) and 3 (7.1%) in class IV. Thirty-two (76.2%) achieved spontaneous vertex delivery (SVD), LSCS was performed in 4 (9.5%) women, 2 (4.8%) women had spontaneous expulsions of dead fetus and 2 (4.8%) had suction and curettage for therapeutic termination of pregnancy on medical grounds. Obstetric complications occurred in 17 (40.4%) women, 5 (11.9%) had medical complications and 3 (7.1%) maternal mortalities occurred. Regarding fetal outcome, 6 (14.3%) infants had intrauterine growth restriction (IUGR), 2 (4.8%) perinatal deaths occurred due to prematurity while there was 1 (2.4%) intrauterine death. Indicated terminations of pregnancy were done for 4 gestations (7.1%). Low birth weight was noted in 12 (28.6%) infants.
Heart disease with pregnancy is a very high risk condition and maternal mortality ratio (MMR) was 7142/100,000 births. The management of these cases should be multidisciplinary to optimize care for these patients and large families be strongly discouraged.
确定孕期及分娩期患有心脏病的女性的胎儿及母体结局。
描述性研究。
2001年3月至2003年2月期间,在伊斯兰堡PIMS妇幼保健中心第二单元妇产科。
纳入研究期间在妇幼保健中心第二单元分娩的42例患有心脏病的孕妇。母体结局指标包括产科及内科并发症和孕产妇死亡率,而胎儿结局指标为早产、宫内生长受限、围产期死亡率、宫内死亡及引产。
平均年龄为27.50±5.17岁(标准差)。42例女性中,33例(78.6%)进行了产前检查,9例(21.4%)未进行产前检查。7例(16.7%)患有先天性心脏病,28例(65.3%)患有风湿性心脏病,其中二尖瓣疾病最为常见。其余7例患有后天性心脏病的女性中,3例(7.1%)患有缺血性心脏病(IHD),1例(2.4%)患有原发性肺动脉高压,2例(4.8%)患有围产期心肌病,1例(2.4%)患有主动脉夹层。根据纽约心脏协会功能分级(NYHA),16例(38.1%)患者无症状(I级),3例(7.1%)为IV级。32例(76.2%)实现了自然头位分娩(SVD),4例(9.5%)女性进行了剖宫产,2例(4.8%)女性自然排出死胎,2例(4.8%)因医学原因进行了刮宫术以终止妊娠。17例(40.4%)女性发生产科并发症,5例(11.9%)发生内科并发症,3例(7.1%)孕产妇死亡。关于胎儿结局,6例(14.3%)婴儿患有宫内生长受限(IUGR),2例(4.8%)围产期死亡是由于早产,1例(2.4%)发生宫内死亡。4例妊娠(7.1%)进行了引产。12例(28.6%)婴儿出生体重低。
妊娠合并心脏病是一种高风险疾病,孕产妇死亡率为7142/10万活产。这些病例的管理应多学科协作,以优化对这些患者的护理,强烈建议避免大家庭。