Doshi Haresh U, Oza Heena V, Tekani Hemali, Modi Kunal
Department of Obstetrics and Gynaecology, BJ Medical College, Ahmedabad 380016.
J Indian Med Assoc. 2010 May;108(5):278-80, 282.
To assess the maternal and perinatal outcome in pregnant women with cardiac disease, a prospective study was carried out among 51 pregnant women with cardiac disease between January 2006 and August 2008 at a tertiary care centre at BJ Medical College, Ahmedabad, Gujarat. Rheumatic cardiac disease (68.62%) with mitral valve involvement (88.57%) was the commonest cardiac disease. In congenital cardiac disease (21.57%) group septal defect was found as the predominant form. Cardiac surgeries were performed in 11 women before pregnancy out of which 7 had balloon valvotomies, 3 had valve replacements and one had corrective tetrology of Fallot surgery. Two valvotomies were safely done during pregnancy. Out of 51 total patients, two women had opted for termination and two were lost to follow-up. Cardiac complications developed in 17.02% of the women, most common being congestive cardiac failure. It was found more in New York Heart Association grades III and IV (p = 0.00001). A total of 68.08% women delivered vaginally and 31.91% delivered by caesarean section. Complication rate was high (33.33%) in caesarean section group (p = 0.05). Maternal and perinatal outcome was good in general with no maternal death and three perinatal deaths. There were more preterm babies (27.7%; p = 0.03) and babies with intra-uterine growth restriction (48.9%; p = 0.65). None of the newborns of the women who had received anticoagulants had any congenital malformation. Rheumatic heart disease still constitutes the major type of heart disease in our country. Maternal and perinatal morbidity increases with increase in New York Heart Association grade. Surgically treated women tolerate pregnancy well. Vaginal delivery is safer and caesarean section should be reserved only for obstetric indications. Maternal and perinatal outcome can be improved by team approach at tertiary care centre.
为评估患有心脏病的孕妇的孕产妇及围产期结局,于2006年1月至2008年8月在古吉拉特邦艾哈迈达巴德市BJ医学院的三级医疗中心,对51名患有心脏病的孕妇进行了一项前瞻性研究。风湿性心脏病(68.62%)伴二尖瓣受累(88.57%)是最常见的心脏病。在先天性心脏病(21.57%)组中,房间隔缺损是主要类型。11名女性在怀孕前接受了心脏手术,其中7例行球囊瓣膜成形术,3例行瓣膜置换术,1例行法洛四联症矫正手术。孕期安全进行了2例瓣膜成形术。51例患者中,2名女性选择了终止妊娠,2名失访。17.02%的女性出现心脏并发症,最常见的是充血性心力衰竭。在纽约心脏协会III级和IV级患者中更为常见(p = 0.00001)。共有68.08%的女性经阴道分娩,31.91%的女性行剖宫产。剖宫产组的并发症发生率较高(33.33%)(p = 0.05)。总体而言,孕产妇及围产期结局良好,无孕产妇死亡,3例围产儿死亡。早产儿较多(27.7%;p = 0.03),胎儿宫内生长受限的婴儿较多(48.9%;p = 0.65)。接受抗凝剂治疗的女性所生新生儿均无先天性畸形。在我国,风湿性心脏病仍然是心脏病的主要类型。孕产妇及围产期发病率随纽约心脏协会分级的增加而增加。接受手术治疗的女性对妊娠耐受性良好。阴道分娩更安全,剖宫产仅应保留用于产科指征。在三级医疗中心采用团队方法可改善孕产妇及围产期结局。