Schelbert Erik B, Rosenthal Gary E, Welke Karl F, Vaughan-Sarrazin Mary S
Division of Cardiovascular Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Circulation. 2005 Oct 11;112(15):2347-53. doi: 10.1161/CIRCULATIONAHA.104.530550. Epub 2005 Oct 3.
Most prior studies of racial differences in the delivery of cardiac care have focused on potential differences in treatment by individual physicians and hospitals. However, differential use of hospitals with variable practice patterns might also contribute to variations in care.
We compared the use of bioprosthetic valves (BPVs) in 78,154 black and white Medicare beneficiaries > or =65 years of age undergoing aortic valve replacement in 904 US hospitals during 1999 through 2001. Generalized linear mixed models were used to account first for differences in patient characteristics and then for differences in hospitals used by black and white patients. BPV use was lower in black patients relative to white patients after adjustment for patient characteristics (relative risk, 0.93; 95% CI, 0.91 to 0.95; P<0.001). However, black patients were more likely to undergo surgery in hospitals in the lowest quintile of BPV use overall (29% versus 20% of white patients; P<0.001). After hospital-level variability in BPV use was accounted for, the use of BPVs was actually somewhat higher in black patients (relative risk, 1.06; 95% CI, 1.04 to 1.09; P<0.001). Model discrimination as measured by the c statistic was markedly higher after the addition of hospital effects (0.80 versus 0.59 for patient characteristics alone; P<0.001).
Accounting for differences in hospitals preferentially used by black and white patients had a major impact on estimating racial differences in the use of BPVs in patients undergoing aortic valve replacement. Hospital-level effects explained a larger proportion of the variation in BPV use than race and other patient characteristics alone.
先前大多数关于心脏护理提供方面种族差异的研究都集中在个体医生和医院治疗中的潜在差异。然而,不同实践模式医院的差异使用也可能导致护理差异。
我们比较了1999年至2001年期间在美国904家医院接受主动脉瓣置换术的78154名年龄≥65岁的黑人和白人医疗保险受益人中生物瓣膜(BPV)的使用情况。使用广义线性混合模型首先考虑患者特征的差异,然后考虑黑人和白人患者使用医院的差异。在调整患者特征后,黑人患者的BPV使用率低于白人患者(相对风险,0.93;95%置信区间,0.91至0.95;P<0.001)。然而,黑人患者在总体BPV使用量最低的五分之一医院中接受手术的可能性更高(29%对白人患者的20%;P<0.001)。在考虑了医院层面BPV使用的变异性后,黑人患者的BPV使用实际上略高一些(相对风险,1.06;95%置信区间,1.04至1.09;P<0.001)。加入医院效应后,用c统计量衡量的模型辨别力明显更高(仅患者特征时为0.80对0.59;P<0.001)。
考虑黑人和白人患者优先使用医院的差异对估计接受主动脉瓣置换术患者BPV使用的种族差异有重大影响。医院层面的效应比种族和其他患者特征单独解释了BPV使用变异的更大比例。