Kieran Kathleen, Roberts William W
University of Michigan Urology Center, Ann Arbor, Michigan 48109, USA.
Curr Opin Nephrol Hypertens. 2005 Nov;14(6):599-603. doi: 10.1097/01.mnh.0000170750.18409.96.
Laparoscopic donor nephrectomy is considered the gold standard for renal donation. In the hands of experienced laparoscopists it provides a safe and equally effective alternative to open nephrectomy, and recipient graft function has been shown to be equivalent regardless of the procurement method utilized. Complication rates and postoperative donor renal function are equivalent to that of open nephrectomy, whereas recovery time is significantly shorter and surgical scars more cosmetic with the laparoscopic approach.
Advances in preoperative imaging and laparoscopic technique have enabled surgeons to broaden the patient population considered for donor nephrectomy. Improved three-dimensional imaging facilitates operative planning and intraoperative dissection, and the retroperitoneoscopic approach has decreased operative time. Acquisition of laparoscopic skills has also enabled surgeons to perform donor nephrectomies on kidneys that previously would have been considered less desirable for donation (e.g. right-sided or with anomalous vasculature).
End-stage renal disease and the need for renal transplantation continue to be major medical concerns in the United States and worldwide. Advances in donor nephrectomy have reduced the demand for organs by increasing the potential organ pool while limiting risk to donors. As imaging and laparoscopic techniques continue to advance, it is anticipated that minimally invasive donor nephrectomy will continue to evolve. This review summarizes the developments to date.
腹腔镜供肾切除术被认为是肾脏捐赠的金标准。在经验丰富的腹腔镜手术医生手中,它为开放性肾切除术提供了一种安全且同样有效的替代方法,并且无论采用何种获取方法,受者的移植肾功能已被证明是相当的。并发症发生率和术后供体肾功能与开放性肾切除术相当,而腹腔镜手术方法的恢复时间明显更短,手术疤痕也更美观。
术前影像学和腹腔镜技术的进步使外科医生能够扩大供肾切除术的适用患者群体。改进的三维成像有助于手术规划和术中解剖,后腹腔镜手术方法减少了手术时间。腹腔镜技术的掌握也使外科医生能够对以前被认为不太适合捐赠的肾脏进行供肾切除术(例如右侧肾脏或血管异常的肾脏)。
终末期肾病和肾移植需求在美国及全球仍然是主要的医疗问题。供肾切除术的进展通过增加潜在器官库同时限制对供体的风险,减少了对器官的需求。随着影像学和腹腔镜技术不断进步,预计微创供肾切除术将继续发展。本综述总结了迄今为止的进展。