Shatalov V I, Shchegolev A V
Anesteziol Reanimatol. 2005 Jul-Aug(4):55-8.
The study included 31 patients with constrictive and stenotic angiopathy (CSAP) that had developed due subarachnoidal hemorrhage. All the patients were operated on within the first 4 days after the moment of blood bleeding. Since the onset of CSAP, Groups 1 (n = 14) 2 (n = 17) received normovolemic and hypervolemic infusion therapy, respectively. In both groups, cerebral circulatory changes were found to depend primarily on cardiac productive parameters. The nature of infusion therapy had no impact on the results of treatment (according to the Glasgow scale). Hypervolemia used in such patients has no advantages over normovolemic water load when hyperdynamic circulation is created when inotropic agents are used.
该研究纳入了31例因蛛网膜下腔出血而发生狭窄性血管病(CSAP)的患者。所有患者均在出血后4天内接受手术。自CSAP发病以来,第1组(n = 14)和第2组(n = 17)分别接受了正常血容量和高血容量输注治疗。在两组中,均发现脑循环变化主要取决于心脏的有效参数。输注治疗的方式对治疗结果(根据格拉斯哥量表)没有影响。当使用正性肌力药物创造高动力循环时,此类患者使用高血容量疗法并不比正常血容量水负荷有优势。