用于不可手术的骨关节炎和软组织风湿病的阿片类药物。
Opioids for non-operable osteoarthritis and soft-tissue rheumatism.
作者信息
Dickson David John
机构信息
James Cook University Hospital, Middlesbrough, UK.
出版信息
Arthritis Res Ther. 2005;7(5):193-4. doi: 10.1186/ar1817. Epub 2005 Aug 25.
Abstract
Reviews of oral opioid trials have shown that many side-effects need to be considered when treating patients with non-operable osteoarthritis and soft-tissue problems. European and American guidelines recommend their use with or without paracetamol. The controversy surrounding the use of non-steroidal anti-inflammatory drugs/cyclo-oxygenase-2 inhibitors is limiting physician and patient choices. There is a great need for alternative medication or ways of using current compounds.
摘要
口服阿片类药物试验的综述表明，在治疗患有不可手术的骨关节炎和软组织问题的患者时，需要考虑许多副作用。欧美指南推荐在使用或不使用对乙酰氨基酚的情况下使用阿片类药物。围绕非甾体抗炎药/环氧化酶-2抑制剂使用的争议限制了医生和患者的选择。非常需要替代药物或使用现有化合物的方法。
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