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抑郁症治疗方案的制定:习得性足智多谋的作用,一项未能重复的研究。

Prescribing therapy for depression: the role of learned resourcefulness, a failure to replicate.

作者信息

Wetzel R D, Murphy G E, Carney R M, Whitworth P, Knesevich M A

机构信息

Department of Psychiatry, Washington University School of Medicine, Louis, Missouri 63110.

出版信息

Psychol Rep. 1992 Jun;70(3 Pt 1):803-7. doi: 10.2466/pr0.1992.70.3.803.

DOI:10.2466/pr0.1992.70.3.803
PMID:1620773
Abstract

Work in 1985 by Simons, Lustman, Wetzel, and Murphy showed that a patient's score on Rosenbaum's self-control scale predicted differential response to treatments for depression, with a high score predicting a good outcome with talking therapy and a low score a good outcome with drug therapy. This study of 37 patients did not replicate those findings. Using the same paradigm, we predicted response correctly 7 times and incorrectly 16 times, a clear failure. A valid method for choosing the best treatment for a patient with major depression remains to be found.

摘要

西蒙斯、勒斯特曼、韦策尔和墨菲在1985年开展的研究表明,患者在罗森鲍姆自我控制量表上的得分可预测其对抑郁症治疗的不同反应,高分预示着谈话疗法会带来良好效果,低分则预示着药物疗法会有良好效果。这项针对37名患者的研究并未重现这些结果。采用相同的模式,我们正确预测反应7次,错误预测16次,显然是失败了。一种为重度抑郁症患者选择最佳治疗方法的有效方法仍有待发现。

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