Guthrie S, Plummer J M, Vaughan L C
Department of Small Animal Medicine and Surgery, Royal Veterinary College, North Mymms, Hatfield, Hertfordshire.
Res Vet Sci. 1992 May;52(3):284-91. doi: 10.1016/0034-5288(92)90026-x.
Twenty-five ununited coronoid processes (UCP) and 24 osteochondritis dissecans (OD) flaps were examined by light and transmission electron microscopy. Chondrocytes showed degenerative changes but remained viable and continued to secrete matrix components, even though the organisation of the matrix was altered. Differences in the histological and ultrastructural appearance of the two lesions tend to suggest that they are two separate disease entities, although they may occur together in the same joint. It is hypothesised that OD results from incorrect cartilage maturation and endochondral ossification. The aetiology of UCP is unclear but there is a possibility of its being a subchondral fracture, with an ineffective fibrous repair in some cases.
对25例未愈合的冠状突和24例剥脱性骨软骨炎皮瓣进行了光镜和透射电镜检查。软骨细胞显示出退行性改变，但仍保持活力并继续分泌基质成分，尽管基质的组织结构发生了改变。这两种病变在组织学和超微结构外观上的差异倾向于表明它们是两种不同的疾病实体，尽管它们可能在同一关节中同时出现。据推测，剥脱性骨软骨炎是由于软骨成熟和软骨内成骨不正确所致。未愈合冠状突的病因尚不清楚，但有可能是软骨下骨折，在某些情况下纤维修复无效。
