Vogt P R, Bauer E P, von Segesser L K, Turina M I
Klinik für Herz- und Gefässchirurgie, Universitätsspital Zürich.
Schweiz Med Wochenschr. 1992 Jun 20;122(25):975-8.
From 1987 to 1990, 37 children underwent surgical correction for tetralogy of Fallot. The mean age was 38.2 months (2-156 months). The indication for right ventricular outflow tract (RVOT) obstruction in 19/37 (51%) children was: hypoplastic pulmonary valve (n = 10), annular hypoplasia (n = 12), RVOT obstruction and hypoplastic pulmonary artery (n = 10). In 18/37 (49%) children, the repair of the RVOT was done without homograft. The RVOT morphology was the only indication for reconstruction with homograft. All other pre-, intra- and postoperative data were identical for both groups. There was no operative or late death. After a mean follow-up of 4.4 months, all 19 children with homograft were in NYHA class I and echocardiographic evaluation showed mild and moderate pulmonary regurgitation in 8 and 4 children respectively. Out of the 18 children without homograft, 16 were in NYHA class I and 2 in NYHA class II. Two children had early postoperative right heart failure. The mean follow-up time in this group was 5.5 months. Echocardiography revealed residual pulmonary regurgitation in 4 children, pulmonary stenosis in 6 and combined residual pulmonary valve defect in 6. If severe malformation of the RVOT or the pulmonary artery is present, a valved homograft is recommended for repair of tetralogy of Fallot. Good morphological and functional results may be achieved.
1987年至1990年期间,37名儿童接受了法洛四联症的外科矫正手术。平均年龄为38.2个月(2至156个月)。19/37(51%)名儿童右心室流出道(RVOT)梗阻的指征为:肺动脉瓣发育不全(n = 10)、瓣环发育不全(n = 12)、RVOT梗阻合并肺动脉发育不全(n = 10)。18/37(49%)名儿童在没有同种异体移植物的情况下进行了RVOT修复。RVOT形态是使用同种异体移植物进行重建的唯一指征。两组的所有其他术前、术中和术后数据均相同。无手术或晚期死亡病例。平均随访4.4个月后,所有19名接受同种异体移植物的儿童心功能均为纽约心脏协会(NYHA)I级,超声心动图评估显示,分别有8名和4名儿童存在轻度和中度肺动脉反流。在18名未使用同种异体移植物的儿童中,16名心功能为NYHA I级,2名心功能为NYHA II级。两名儿童术后早期出现右心衰竭。该组的平均随访时间为5.5个月。超声心动图显示,4名儿童存在残余肺动脉反流,6名儿童存在肺动脉狭窄,6名儿童存在合并的残余肺动脉瓣缺损。如果存在RVOT或肺动脉的严重畸形,建议使用带瓣同种异体移植物修复法洛四联症。可取得良好的形态和功能结果。