Focus on molecules: lumican.
作者信息
Kao Winston W-Y, Funderburgh James L, Xia Ying, Liu Chia-Yang, Conrad Gary W
机构信息
Department of Ophthalmology, University of Cincinnati, Cincinnati, OH, USA.
出版信息
Exp Eye Res. 2006 Jan;82(1):3-4. doi: 10.1016/j.exer.2005.08.012. Epub 2005 Oct 5.
Abstract
摘要
相似文献
1
Focus on molecules: lumican.聚焦分子：核心蛋白聚糖
Exp Eye Res. 2006 Jan;82(1):3-4. doi: 10.1016/j.exer.2005.08.012. Epub 2005 Oct 5.
2
Structure and biological functions of keratan sulfate proteoglycans.硫酸角质素蛋白聚糖的结构与生物学功能
EXS. 1994;70:101-22. doi: 10.1007/978-3-0348-7545-5_7.
3
Modulation of keratan sulfate synthesis on lumican by the action of cytokines on human articular chondrocytes.细胞因子对人关节软骨细胞作用下硫酸角质素在核心蛋白聚糖上合成的调节。
Matrix Biol. 1999 Aug;18(4):381-90. doi: 10.1016/s0945-053x(99)00033-5.
4
Epithelial repair: roles of extracellular matrix.上皮修复：细胞外基质的作用
Cornea. 2002 Mar;21(2 Suppl 1):S23-9. doi: 10.1097/00003226-200203001-00006.
5
Lumican is required for neutrophil extravasation following corneal injury and wound healing.层粘连蛋白对于角膜损伤和伤口愈合后的中性粒细胞渗出是必需的。
J Cell Sci. 2010 Sep 1;123(Pt 17):2987-95. doi: 10.1242/jcs.068221. Epub 2010 Aug 10.
6
Lumican promotes corneal epithelial wound healing.角膜蛋白聚糖促进角膜上皮伤口愈合。
Methods Mol Biol. 2012;836:285-90. doi: 10.1007/978-1-61779-498-8_18.
7
Identification of the N-linked oligosaccharide sites in chick corneal lumican and keratocan that receive keratan sulfate.鸡角膜核心蛋白聚糖和角蛋白聚糖中接受硫酸角质素的N-连接寡糖位点的鉴定
J Biol Chem. 1998 Apr 17;273(16):9615-21. doi: 10.1074/jbc.273.16.9615.
8
Altered KSPG expression by keratocytes following corneal injury.角膜损伤后角膜细胞中角膜硫酸蛋白聚糖（KSPG）表达的改变。
Mol Vis. 2003 Nov 21;9:615-23.
9
Lumican, a small leucine-rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes.富含亮氨酸的小分子硫酸角质素蛋白聚糖——角膜蛋白聚糖，由人类黑色素瘤细胞表达和分泌，而非正常黑素细胞。
IUBMB Life. 2006 Oct;58(10):606-10. doi: 10.1080/15216540600951605.
10
The role of SLRP-proteoglycans in osteosarcoma pathogenesis.小分子富含亮氨酸蛋白聚糖在骨肉瘤发病机制中的作用。
Connect Tissue Res. 2008;49(3):235-8. doi: 10.1080/03008200802147589.
引用本文的文献
1
Lumican/Lumikine Promotes Healing of Corneal Epithelium Debridement by Upregulation of EGFR Ligand Expression via Noncanonical Smad-Independent TGFβ/TBRs Signaling.纤连蛋白/Lumikine 通过非经典 Smad 独立的 TGFβ/TBRs 信号上调 EGFR 配体表达促进角膜上皮清创愈合。
Cells. 2024 Sep 24;13(19):1599. doi: 10.3390/cells13191599.
2
Biomarkers Identification in the Microenvironment of Oral Squamous Cell Carcinoma: A Systematic Review of Proteomic Studies.口腔鳞状细胞癌微环境中的生物标志物鉴定：蛋白质组学研究的系统评价。
Int J Mol Sci. 2024 Aug 16;25(16):8929. doi: 10.3390/ijms25168929.
3
Twisting the theory on the origin of human umbilical cord coiling featuring monozygotic twins.扭转关于具有同卵双胞胎特征的人类脐带缠绕起源的理论。
Life Sci Alliance. 2024 Jun 3;7(8). doi: 10.26508/lsa.202302543. Print 2024 Aug.
4
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing.理性设计与合成锚定肽促进角膜伤口愈合。
Ocul Surf. 2023 Oct;30:168-178. doi: 10.1016/j.jtos.2023.09.007. Epub 2023 Sep 22.
5
Control of tissue homeostasis by the extracellular matrix: Synthetic heparan sulfate as a promising therapeutic for periodontal health and bone regeneration.细胞外基质对组织稳态的调控：合成肝素硫酸作为牙周健康和骨再生有前景的治疗剂。
Periodontol 2000. 2024 Feb;94(1):510-531. doi: 10.1111/prd.12515. Epub 2023 Aug 24.
6
Small leucine rich proteoglycans: Biology, function and their therapeutic potential in the ocular surface.富含亮氨酸的小分子蛋白聚糖：生物学、功能及其在眼表的治疗潜力
Ocul Surf. 2023 Jul;29:521-536. doi: 10.1016/j.jtos.2023.06.013. Epub 2023 Jun 22.
7
Using Cumulus Cell Biopsy as a Non-Invasive Tool to Access the Quality of Bovine Oocytes: How Informative Are They?利用卵丘细胞活检作为评估牛卵母细胞质量的非侵入性工具：它们的信息量有多大？
Animals (Basel). 2022 Nov 11;12(22):3113. doi: 10.3390/ani12223113.
8
Metabolite, protein, and tissue dysfunction associated with COVID-19 disease severity.与 COVID-19 疾病严重程度相关的代谢物、蛋白质和组织功能障碍。
Sci Rep. 2022 Jul 16;12(1):12204. doi: 10.1038/s41598-022-16396-9.
9
Differential MMP-14 Targeting by Lumican-Derived Peptides Unraveled by In Silico Approach.通过计算机模拟方法揭示的卢米卡衍生肽对基质金属蛋白酶-14的差异性靶向作用
Cancers (Basel). 2021 Sep 30;13(19):4930. doi: 10.3390/cancers13194930.
10
Extracellular Matrix Deposition and Remodeling after Corneal Alkali Burn in Mice.小鼠角膜碱烧伤后细胞外基质的沉积与重塑
Int J Mol Sci. 2021 May 27;22(11):5708. doi: 10.3390/ijms22115708.
本文引用的文献
1
Keratocan, a cornea-specific keratan sulfate proteoglycan, is regulated by lumican.角膜蛋白聚糖是一种角膜特异性硫酸角质素蛋白聚糖，受亮蛋白聚糖调控。
J Biol Chem. 2005 Jul 8;280(27):25541-7. doi: 10.1074/jbc.M500249200. Epub 2005 Apr 22.
2
Roles of lumican and keratocan on corneal transparency.亮蛋白聚糖和角膜蛋白聚糖对角膜透明度的作用。
Glycoconj J. 2002 May-Jun;19(4-5):275-85. doi: 10.1023/A:1025396316169.
3
Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma.富含亮氨酸蛋白聚糖基因敲除小鼠的角膜混浊：后弹力层中胶原纤维结构和排列的缺陷
Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3365-73.
4
Macrophage receptors for lumican. A corneal keratan sulfate proteoglycan.角膜硫酸角质素蛋白聚糖（纤连蛋白聚糖）的巨噬细胞受体。
Invest Ophthalmol Vis Sci. 1997 May;38(6):1159-67.
Zotero 插件