Savino Francesco, Castagno Emanuele, Bretto Roberta, Brondello Cristina, Palumeri Elisabetta, Oggero Roberto
Department of Paediatrics, University of Turin, Turin, Italy.
Acta Paediatr Suppl. 2005 Oct;94(449):129-32. doi: 10.1111/j.1651-2227.2005.tb02169.x.
To evaluate the association between infantile colic and gastrointestinal, allergic and psychological disorders in childhood.
A prospective study was conducted on 103 infants aged 31-87 d. After 10 y, between 2001 and 2003, the children were recalled and a paediatrician evaluated the selected disorders by anamnesis, medical examination, laboratory tests and parent interviews.
Of the 103 infants enrolled, 96 completed the study. There was an association between infantile colic and recurrent abdominal pain (p=0.001) and allergic disorders: allergic rhinitis, conjunctivitis, asthmatic bronchitis, pollenosis, atopic eczema and food allergy (p<0.05). Sleep disorders, fussiness, aggressiveness and feelings of supremacy are more frequent in children who suffered from colic during early infancy (p<0.05). A family history of gastrointestinal diseases and atopic diseases was significantly higher in infants with colic than in controls (p<0.05).
Susceptibility to recurrent abdominal pain, allergic and psychological disorders in childhood may be increased by infantile colic. Our findings confirm that severe infantile colic might be the early expression of some of the most common disorders in childhood.
评估婴儿腹绞痛与儿童期胃肠道、过敏性及心理障碍之间的关联。
对103名年龄在31至87天的婴儿进行了一项前瞻性研究。在2001年至2003年期间，10年后召回这些儿童，由一名儿科医生通过问诊、体格检查、实验室检查及与家长访谈来评估选定的疾病。
在纳入研究的103名婴儿中，96名完成了研究。婴儿腹绞痛与复发性腹痛（p = 0.001）及过敏性疾病（变应性鼻炎、结膜炎、哮喘性支气管炎、花粉症、特应性皮炎和食物过敏，p < 0.05）之间存在关联。在婴儿早期患腹绞痛的儿童中，睡眠障碍、烦躁、攻击性及优越感更为常见（p < 0.05）。腹绞痛婴儿的胃肠道疾病和特应性疾病家族史显著高于对照组（p < 0.05）。
婴儿腹绞痛可能会增加儿童期复发性腹痛、过敏性及心理障碍的易感性。我们的研究结果证实，严重的婴儿腹绞痛可能是儿童期一些最常见疾病的早期表现。
